Tag Archives: Knockout Mice

Preservation of cardiac function and attenuation of remodelling in transient receptor potential vanilloid 4 knockout mice following myocardial infarction

Turner G, Bao W, Jucker B, Lepore J, Willette R. Preservation of cardiac function and attenuation of remodelling in transient receptor potential vanilloid 4 knockout mice following myocardial infarction. J Clin Exp Cardiolog. March 2015;6(366):2. Full Text – Open Access Publication Date March 2015 How Analyze was Used “Cardiac functional parameters for the left ventricle…

p27kip1 Knockout enhances collateralization in response to hindlimb ischemia

Ankri-Eliahoo G, Weitz K, Cox TC, Tang GL. p27kip1 Knockout enhances collateralization in response to hindlimb ischemia. J Vasc Surg. February 2015. Publication Date February 2015 How Analyze was Used “Reconstruction of the raw data images was done with NRecon V1.6.1.0 (SkyScan) software and analyzed with Analyze 10.0 …, MATLAB R2013a … and CTan (SkyScan).”…

Mutations in the Latent TGF-beta Binding Protein 3 (LTBP3) gene cause brachyolmia with amelogenesis imperfecta

Huckert M, Stoetzel C, Morkmued S, Laugel-Haushalter V, Geoffroy V, Muller J, Clauss F, Prasad MK, Obry F, Raymond JL, Switala M, Alembik Y, Soskin S, Mathieu E, Hemmerlé J, Weickert JL, Dabovic B, Rifkin DB, Dheedene A, Boudin E, Caluseriu O, Cholette MC, McLeod R, Antequera R, Gellé MP, Coeuriot JL, Jacquelin LF, Bailleul-Forestier…

Numerical metrics for automated quantification of interstitial cell of Cajal network structural properties

Gao J, Du P, O’Grady G, Archer R, Farrugia G, Gibbons SJ, Cheng LK. Numerical metrics for automated quantification of interstitial cell of Cajal network structural properties. J R Soc Interface. September 2013;10(86):20130421. Full Text – Open Access Publication Date September 2013 How Analyze was Used “Confocal image slices were sequentially taken throughout the transmural…

Renal tumours in a Tsc1+/- mouse model show epigenetic suppression of organic cation transporters Slc22a1, Slc22a2 and Slc22a3, and do not respond to metformin

Yang J, Kalogerou M, Gallacher J, Sampson JR, Shen MH. Renal tumours in a Tsc1+/- mouse model show epigenetic suppression of organic cation transporters Slc22a1, Slc22a2 and Slc22a3, and do not respond to metformin. Eur J Cancer. April 2013;49(6):1479-1490. Publication Date April 2013 How Analyze was Used “The volumes of renal lesions were measured using…

RALBP1/RLIP76 depletion in mice suppresses tumor growth by inhibiting tumor neovascularization

Lee S, Wurtzel JGT, Singhal SS, Awasthi S, Goldfinger LE. RALBP1/RLIP76 depletion in mice suppresses tumor growth by inhibiting tumor neovascularization. Cancer Res. October 2012;72(20):5165-5173. Full Text – Open Access Publication Date October 2012 How Analyze was Used “Samples were positioned on a computer-controlled rotation stage and scanned 180° around the vertical axis in rotation…

Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice

Zhang X, Urbieta-Caceres VH, Eirin A, Bell CC, Crane JA, Tang H, Jordan KL, Oh YK, Zhu XY, Korsmo MJ, Bachar AR, Cohen P, Lerman A, Lerman LO. Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice. Life Sci. September 2012;91(5-6):199-206. Full Text – Open Access Publication Date September 2012 How Analyze…

Mixed testicular atrophy related to atherosclerosis: first lessons from the ApoE(-/-)/ LDL receptor(-/-) double knockout mouse model

Langheinrich AC, Paradowska A, Kilinski R, Kampschulte M, Steinfeld K, Altinkilic B, Steger K, Stieger P, Bergmann M, Weidner W. Mixed testicular atrophy related to atherosclerosis: first lessons from the ApoE(-/-)/ LDL receptor(-/-) double knockout mouse model. Int J Androl. August 2012;35(4):562-571. Publication Date August 2012 How Analyze was Used “The resulting 3D images were…

Effect of the anti-oxidant tempol on fetal growth in a mouse model of fetal growth restriction

Stanley JL, Andersson IJ, Hirt CJ, Moore L, Dilworth MR, Chade AR, Sibley CP, Davidge ST, Baker PN. Effect of the anti-oxidant tempol on fetal growth in a mouse model of fetal growth restriction. Biol Reprod. July 2012;87(1):25, 21-28. Full Text – Open Access Publication Date July 2012 How Analyze was Used “Three-dimensional volume images…

Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease

Masyuk TV, Radtke BN, Stroope AJ, Banales JM, Masyuk AI, Gradilone SA, Gajdos GB, Chandok N, Bakeberg JL, Ward CJ, Ritman EL, Kiyokawa H, LaRusso NF. Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease. Gastroenterology. March 2012;142(3):622-633.e624. Full Text – Open Access Publication Date March 2012 How Analyze…