AnalyzeDirect Zhang X, Urbieta-Caceres VH, Eirin A, Bell CC, Crane JA, Tang H, Jordan KL, Oh YK, Zhu XY, Korsmo MJ, Bachar AR, Cohen P, Lerman A, Lerman LO. Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice. Life Sci. September 2012;91(5-6):199-206.
Full Text – Open Access
Publication Date
September 2012
How Analyze was Used
“Three-dimensional 20µm on-a-side images were then reconstructed and analyzed with the Analyze™ software package (Analyze 10.0…)(Chade et al. 2006).”
Keywords
Animals
Apolipoproteins E/genetics
Apoptosis/drug effects
Atherosclerosis/drug therapy/physiopathology
Blotting, Western
Disease Progression
Female
Hypercholesterolemia/drug therapy/physiopathology
Inflammation/drug therapy/physiopathology
Intracellular Signaling Peptides and Proteins/metabolism/physiology
Kidney/blood supply/drug effects/metabolism
Kidney Diseases/drug therapy/etiology
Mice
Mice, Inbred C57BL
Mice, Knockout
Microvessels/drug effects
Neovascularization, Pathologic/drug therapy
Author Affiliation(s)
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, US. (XZ, VHUC, AE, CCB, JAC, HT, KLJ, XYZ, MJK, LOL)
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, US. (YKO, ARB, AB, LOL)
Department of Pediatrics, Division of Endocrinology, UCLA, 405 Hilgard Avenue, Los Angeles, CA 90095, US. (PC)
ID# 529
Tags: Animals, Apolipoproteins E/genetics, Apoptosis/drug effects, Atherosclerosis/drug therapy/physiopathology, Disease Progression, Female, Hypercholesterolemia/drug therapy/physiopathology, Inbred C57BL Mice, Inflammation/drug therapy/physiopathology, Intracellular Signaling Peptides and Proteins/metabolism/physiology, Kidney Diseases/drug therapy/etiology, Kidney/blood supply/drug effects/metabolism, Knockout Mice, Mice, Microvessels/drug effects, Pathologic Neovascularization/drug therapy, Western Blotting