Tag Archives: Apoptosis/drug effects

The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth

Kurenova E, Liao J, He DH, Hunt D, Yemma M, Bshara W, Seshadri M, Cance WG. The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth. Oncotarget. October 2013;4(10):1632-1646. Full Text – Open Access Publication Date October 2013 How Analyze was Used “Image processing and analysis were carried out using commercially available…

Quantitative receptor-based imaging of tumor proliferation with the sigma-2 ligand [(18)F]ISO-1

Shoghi KI, Xu J, Su Y, He J, Rowland D, Yan Y, Garbow JR, Tu Z, Jones LA, Higashikubo R, Wheeler KT, Lubet RA, Mach RH, You M. Quantitative receptor-based imaging of tumor proliferation with the sigma-2 ligand [(18)F]ISO-1. PLoS One. September 2013;8(9):e74188. Full Text – Open Access Publication Date September 2013 How Analyze was…

Renoprotective effects of hepatocyte growth factor in the stenotic kidney

Stewart N, Chade AR. Renoprotective effects of hepatocyte growth factor in the stenotic kidney. Am J Physiol Renal Physiol. March 2013;304(6):F625-633. Full Text – Open Access Publication Date March 2013 How Analyze was Used “The kidney samples were scanned at 0.3-in. increments using a micro-CT scanner and reconstructed at 9-μm resolution for subsequent analysis using…

Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice

Zhang X, Urbieta-Caceres VH, Eirin A, Bell CC, Crane JA, Tang H, Jordan KL, Oh YK, Zhu XY, Korsmo MJ, Bachar AR, Cohen P, Lerman A, Lerman LO. Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice. Life Sci. September 2012;91(5-6):199-206. Full Text – Open Access Publication Date September 2012 How Analyze…

Endothelin-A receptor blockade slows the progression of renal injury in experimental renovascular disease

Kelsen S, Hall JE, Chade AR. Endothelin-A receptor blockade slows the progression of renal injury in experimental renovascular disease. Am J Physiol Renal Physiol. July 2011;301(1):F218-225. Full Text – Open Access Publication Date July 2011 How Analyze was Used “The kidney samples were scanned at 0.3° increments using a micro-CT scanner and reconstructed at 9-μm…

Cooperation of the agonistic DR5 antibody apomab with chemotherapy to inhibit orthotopic lung tumor growth and improve survival

Jin H, Yang R, Ross J, Fong S, Carano R, Totpal K, Lawrence D, Zheng Z, Koeppen H, Stern H, Schwall R, Ashkenazi A. Cooperation of the agonistic DR5 antibody apomab with chemotherapy to inhibit orthotopic lung tumor growth and improve survival. Clin Cancer Res. December 2008;14(23):7733-7740. Full Text – Open Access Publication Date December…