Tag Archives: Knockout Mice

Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse

Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RAD, Peterson AS, Solloway MJ. Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. May 2011;193(5):935-951. Full Text – Open Access Publication Date May 2011 How Analyze was Used “The micro-CT scans…

Quantitative CT imaging of the spatio-temporal distribution patterns of vasa vasorum in aortas of aloe-/-/LDL-/- double knockout mice

Kampschulte M, Brinkmann A, Stieger P, Sedding DG, Dierkes C, Bohle RM, Krombach G, Ritman EL, Langheinrich AC. Quantitative CT imaging of the spatio-temporal distribution patterns of vasa vasorum in aortas of apoE-/-/LDL-/- double knockout mice. Atherosclerosis. October 2010;212(2):444-450. Publication Date October 2010 How Analyze was Used “Samples were scanned with a cubic voxel resolution…

Atherosclerosis, inflammation and lipoprotein glomerulopathy in kidneys of aloe-/-/LDL-/- double knockout mice

Langheinrich AC, Kampschulte M, Scheiter F, Dierkes C, Stieger P, Bohle RM, Weidner W. Atherosclerosis, inflammation and lipoprotein glomerulopathy in kidneys of apoE, -/-/LDL-/- double knockout mice. BMC Nephrol. August 2010;11:18. Full Text – Open Access Publication Date August 2010 How Analyze was Used “First, the kidneys were scanned in toto by a Micro-CT system…

Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection

Carlsson F, Kim J, Dumitru C, Barck KH, Carano RAD, Sun M, Diehl L, Brown EJ. Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection. PLoS Pathog. May 2010;6(5):e1000895. Full Text – Open Access Publication Date May 2010 How Analyze was Used “Mean bone volume within the segmented bone was measured for each vertebra, and…

Tissue-specific mathematical models of slow wave entrainment in wild-type and 5-HT2B knockout mice with altered interstitial cells of Cajal networks

Du P, O’Grady G, Gibbons SJ, Yassi R, Lees-Green R, Farrugia G, Cheng LK, Pullan AJ. Tissue-specific mathematical models of slow wave entrainment in wild-type and 5-HT2B knockout mice with altered interstitial cells of Cajal networks. Biophys J. May 2010;98(9):1772-1781. Full Text – Open Access Publication Date May 2010 How Analyze was Used “Stacks of…

Inhibition of the p38 MAP kinase in vivo improves number and functional activity of vasculogenic cells and reduces atherosclerotic disease progression

Seeger FH, Sedding D, Langheinrich AC, Haendeler J, Zeiher AM, Dimmeler S. Inhibition of the p38 MAP kinase in vivo improves number and functional activity of vasculogenic cells and reduces atherosclerotic disease progression. Basic Res Cardiol. May 2010;105(3):389-397. Publication Date May 2010 How Analyze was Used “For better anatomical orientation, the aorta and the heart…

Atherosclerosis, inflammation and lipoprotein glomerulopathy in kidneys of ApoE-/-/LDL-/-double knockout mice

Scheiter F, Langheinrich A, Kampschulte M, Dierkes C, Stieger P, Bohle R, Weidner W. Atherosclerosis, inflammation and lipoprotein glomerulopathy in kidneys of ApoE-/-/LDL-/- double knockout mice. Paper presented at: Skyscan User Meeting; April 2010; Mechelen, BE. Full Text – Open Access Publication Date April 2010 How Analyze was Used “The resulting 3D images were displayed using…

Pharmacological inhibition of C-C chemokine receptor 2 decreases macrophage infiltration in the aortic root of the human C-C chemokine receptor 2/apolipoprotein E-/- mouse: magnetic resonance imaging assessment

Olzinski AR, Turner GH, Bernard RE, Karr H, Cornejo CA, Aravindhan K, Hoang B, Ringenberg MA, Qin P, Goodman KB, Willette RN, Macphee CH, Jucker BM, Sehon CA, Gough PJ. Pharmacological inhibition of C-C chemokine receptor 2 decreases macrophage infiltration in the aortic root of the human C-C chemokine receptor 2/apolipoprotein E-/- mouse: magnetic resonance…

Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function

Trimborn M, Ghani M, Walther DJ, Dopatka M, Dutrannoy V, Busche A, Meyer F, Nowak S, Nowak J, Zabel C, Klose J, Esquitino V, Garshasbi M, Kuss AW, Ropers HH, Mueller S, Poehlmann C, Gavvovidis I, Schindler D, Sperling K, Neitzel H. Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1…

Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumor-derived endothelial cells and tumor angiogenesis in vivo

Chung I, Han G, Seshadri M, Gillard BM, Yu WD, Foster BA, Trump DL, Johnson CS. Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumor-derived endothelial cells and tumor angiogenesis in vivo. Cancer Res. February 2009;69(3):967-975. Full Text – Open Access Publication Date February 2009 How Analyze was Used “Vessel lumen…