Analyze Publications Database

Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function

Trimborn M, Ghani M, Walther DJ, Dopatka M, Dutrannoy V, Busche A, Meyer F, Nowak S, Nowak J, Zabel C, Klose J, Esquitino V, Garshasbi M, Kuss AW, Ropers HH, Mueller S, Poehlmann C, Gavvovidis I, Schindler D, Sperling K, Neitzel H. Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function. PLoS One. February 2010;5(2):e9242.

Full Text – Open Access

Publication Date
February 2010

How Analyze was Used
“Calculation of brain volume was carried out using Analyze 5.0 software (AnalyzeDirect, Inc.; Lenexa USA).”

Keywords
Animals
Brain/metabolism/pathology
Cell Proliferation
Cells, Cultured
Chromosomal Proteins, Non-Histone/deficiency/genetics/physiology
Chromosome Breakage
Chromosomes, Mammalian/genetics
DNA Damage
Electrophoresis, Gel, Two-Dimensional
Female
Fibroblasts/cytology/metabolism
Gene Expression Profiling
Humans
Magnetic Resonance Imaging (MRI)
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Mice, Knockout
Models, Animal
Oligonucleotide Array Sequence Analysis
Proteomics
Survival Analysis

Author Affiliation(s)
Institute for Medical Genetics, Charité – Universitätsmedizin Berlin, Berlin, Germany. (MT, AB, FM)

Institute of Human Genetics, Charité – Universitätsmedizin Berlin, Berlin, Germany. (MG, VD, SN, JN, CZ, JK, VE, CP, KS, HN)

Max Planck Institute for Molecular Genetics, Berlin, Germany. (DJW, MD, MG, AWK, HHR)

Center for Stroke Research Berlin, Charité – Universitätsmedizin Berlin, Berlin, Germany. (SM)

Institute of Human Genetics, University Wuerzburg, Wuerzburg, Germany. (IG, DS)

ID# 1034

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