The Analyze Blog

MicroCT Analysis of COPD-Related Bone Loss

MicroCT Bone Analysis

Preclinical imaging using microCT is a critical part of the drug discovery process, and  allows significant insights into oncology, cardiovascular diseases, pulmonary diseases and orthopedics. While it is known that chronic obstructive pulmonary disease (COPD) and bone loss are related, almost all of the pathological mechanisms of COPD-related osteoporosis are unknown. A recent study by researchers…

Adipose Tissue Classification and Quantification from MR and CT Imaging

The study of adipose tissue is motivated by the negative consequences of obesity. Countless studies have reported that obesity is associated with an increased risk of heart disease, diabetes and other gastrointestinal diseases, and certain cancers. A search of the term “fat” in the Analyze Publications Database returns over 150 fat-related research articles in which…

Reducing CT radiation dose in liver cancer imaging

CT Liver Tumor

Recent improvements in the diagnosis and treatment of hepatocellular carcinoma (HCC), the most common type of primary liver cancer, have resulted from the use of CT perfusion imaging. This technique provides better tumor characterization by quantifying hepatic arterial blood flow as well as the morphology of the tumor. One of the drawbacks of this technique…

Nasal strips and decongestants: how do they provide relief from nasal congestion?

Nasal Congestion

Nasal congestion, often triggered by allergic reactions and common colds, is caused by inflammation of the membranes lining the nasal passage, resulting in nasal blockage. Besides the breathing difficulties associated with this condition, nasal congestion also leads to reduced sense of smell, reduced feelings of well being, and an increased incidence of sleep apnea. Nasal…

Anterior Cingulate Cortex and Hippocampal Volumes in Depressed Youths

Depressed Youth

Major depression disorder is a mental health condition in which unrelenting feelings such as sadness, hopelessness, anger, or frustration persist for prolonged periods of time and interfere with a person’s daily life. Although major depression arises most commonly in early adulthood, anyone can develop major depression disorder, including children and teenagers. While depression has been…

Fat Depots and Metabolic Syndrome Risk in Black African Young Adults

Metabolic syndrome is a group of risk factors — increased blood pressure, a high blood sugar level, excess body fat around the waist, and abnormal cholesterol levels — that occur together, increasing risk of heart disease, stroke, and diabetes. Several studies have shown that abdominal visceral adipose tissue (VAT) accumulation plays an important role in…

Cerebral Perfusion Pressure in Intracerebral Hemorrhage

Intracerebral hemorrhage accounts for approximately only 12% of all strokes, but it is one of the most disabling forms. The high rate of morbidity and mortality associated with intracerebral hemorrhage has prompted investigations for new medical and surgical therapies. This syndrome occurs when a blood vessel within the brain ruptures, allowing blood to leak inside the…

Total Kidney Volume Measurement in Kidney Disease Progression

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited condition caused by a genetic fault that disrupts normal development of the kidneys. The main function of the kidneys is to filter out waste products from the blood and release them from the body as urine, ADPKD compromises this process. The final stage of the disease…

Biomarkers of Tumor Vascularity in Glioblastoma Multiforme

Increased vascularity is a pivotal event in tumor progression and has prognostic meaning in numerous cancers. Recently developed agents have been designed to target and inhibit angiogenesis factors, preventing the formation of new blood vessels that supply the tumor and allow cancer cells to survive and multiply. Glioblastoma multiforme is the most aggressive and infiltrative type of…

Deep Brain Stimulation for Gait Disturbance in Parkinson’s Disease

Parkinson’s disease is a progressive disorder of the nervous system caused by the loss of dopamine-producing brain cells. Gait disturbance and balance impairment are some of the most incapacitating symptoms of this condition. Several clinical studies have shown that electrical stimulation of the pedunculopontine tegmental nucleus (PPTg), an area of the brain involved in many…