Tag Archives: Transgenic Mice

Quantitative CT imaging of the spatio-temporal distribution patterns of vasa vasorum in aortas of aloe-/-/LDL-/- double knockout mice

Kampschulte M, Brinkmann A, Stieger P, Sedding DG, Dierkes C, Bohle RM, Krombach G, Ritman EL, Langheinrich AC. Quantitative CT imaging of the spatio-temporal distribution patterns of vasa vasorum in aortas of apoE-/-/LDL-/- double knockout mice. Atherosclerosis. October 2010;212(2):444-450. Publication Date October 2010 How Analyze was Used “Samples were scanned with a cubic voxel resolution…

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

Yu T, Li Z, Jia Z, Clapcote SJ, Liu C, Li S, Asrar S, Pao A, Chen R, Fan N, Carattini-Rivera S, Bechard AR, Spring S, Henkelman RM, Stoica G, Matsui S, Nowak NJ, Roder JC, Chen C, Bradley A, Yu YE. A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic…

Brain phenotypes in two FGFR2 mouse models for Apert syndrome

Aldridge K, Hill CA, Austin JR, Percival C, Martinez-Abadias N, Neuberger T, Wang Y, Jabs EW, Richtsmeier JT. Brain phenotypes in two FGFR2 mouse models for Apert syndrome. Dev Dyn. March 2010;239(3):987-997. Full Text – Open Access Publication Date March 2010 How Analyze was Used “The 3D coordinate locations of neuroanatomical landmarks were recorded for…

Pharmacological inhibition of C-C chemokine receptor 2 decreases macrophage infiltration in the aortic root of the human C-C chemokine receptor 2/apolipoprotein E-/- mouse: magnetic resonance imaging assessment

Olzinski AR, Turner GH, Bernard RE, Karr H, Cornejo CA, Aravindhan K, Hoang B, Ringenberg MA, Qin P, Goodman KB, Willette RN, Macphee CH, Jucker BM, Sehon CA, Gough PJ. Pharmacological inhibition of C-C chemokine receptor 2 decreases macrophage infiltration in the aortic root of the human C-C chemokine receptor 2/apolipoprotein E-/- mouse: magnetic resonance…

Use of magnetic resonance imaging for anatomical phenotyping of the R6/2 mouse model of Huntington’s disease

Sawiak SJ, Wood NI, Williams GB, Morton AJ, Carpenter TA. Use of magnetic resonance imaging for anatomical phenotyping of the R6/2 mouse model of Huntington’s disease. Neurobiol Dis. January 2009;33(1):12-19. Publication Date January 2009 How Analyze was Used “Analyze 7.5 … was used to delineate each structure manually, defining for each a region of interest…

Diet supplement CoQ10 delays brain atrophy in aged transgenic mice with mutations in the amyloid precursor protein: an in vivo volume MRI study

Li G, Jack CR, Yang XF, Yang ES. Diet supplement CoQ10 delays brain atrophy in aged transgenic mice with mutations in the amyloid precursor protein: an in vivo volume MRI study. Biofactors. December 2008;32(1-4):169-178. Publication Date December 2008 How Analyze was Used “The hemispheric and hippocampal volumes were delineated with manual region of interest (ROI)…

Targeting Alzheimer’s plaques with Dysprosium based probes

Wadghiri Y, Douadi M, Yang J, Utku Y, Kirshenbaum K, Wisniewski T. Targeting Alzheimer’s plaques with Dysprosium based probes. Paper presented at: 16th Scientific Meeting, International Society for Magnetic Resonance in Medicine; May 2008, Toronto. Publication Date May 2008 How Analyze was Used “The isotropic voxels obtained facilitated comparison between brain datasets and co-registration with…

Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models

Desnoyers LR, Pai R, Ferrando RE, Hötzel K, Le T, Ross J, Carano R, D’Souza A, Qing J, Mohtashemi I, Ashkenazi A, French DM. Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models. Oncogene. January 2008;27(1):85-97. Full Text – Open Access Publication Date January 2008 How Analyze was Used…

Neuroprotective effect of Coenzyme Q10 on ischemic hemisphere in aged mice with mutations in the amyloid precursor protein

Li G, Zou L, Jack CR, Jr., Yang Y, Yang ES. Neuroprotective effect of Coenzyme Q10 on ischemic hemisphere in aged mice with mutations in the amyloid precursor protein. Neurobiol Aging. June 2007;28(6):877-882. Publication Date June 2007 How Analyze was Used “The volume of each infarct was delineated with manual region of interest (ROI) tracing…

Imaging cellular responses to mechanical stimuli within three-dimensional tissue constructs

Tan W, Vinegoni C, Norman JJ, Desai TA, Boppart SA. Imaging cellular responses to mechanical stimuli within three-dimensional tissue constructs. Microsc Res Tech. April 2007;70(4):361-371. Publication Date April 2007 How Analyze was Used “Three-dimensional visualization of the engineered tissue constructs was achieved by volume rendering the image stacks of OCM and MPM data using 3D…