AnalyzeDirect Aldridge K, Hill CA, Austin JR, Percival C, Martinez-Abadias N, Neuberger T, Wang Y, Jabs EW, Richtsmeier JT. Brain phenotypes in two FGFR2 mouse models for Apert syndrome. Dev Dyn. March 2010;239(3):987-997.
Full Text – Open Access
Publication Date
March 2010
How Analyze was Used
“The 3D coordinate locations of neuroanatomical landmarks were recorded for 45 mice (ten Fgfr2+/S252W and 11 of their wild-type littermates, and 14 Fgfr2+/P253R and ten of their wild-type littermates) from MRM images using Analyze 9.0 (Robb et al., 1989).”
Keywords
Acrocephalosyndactylia/genetics
Animals
Brain/embryology
Craniosynostoses/genetics
Disease Models, Animal
Gene Expression Regulation, Developmental
Magnetic Resonance Spectroscopy
Mice
Mice, Inbred C57BL
Mice, Transgenic
Mutation
Phenotype
Receptor, Fibroblast Growth Factor, Type 2/metabolism
Time Factors
Tomography, X-Ray Computed/methods
Author Affiliation(s)
Department of Pathology and Anatomical Sciences, University of Missouri-School of Medicine, Columbia, MO, US. (KA, CAH, JRA)
Department of Anthropology, Pennsylvania State University, University Park, PA, US. (CP, NMA, JTR)
Huck Institutes of the Life Sciences, Pennsylvania State University, Hershey, PA, US. (TN)
Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, NY, US. (YW, EWJ)
ID# 967
Tags: Acrocephalosyndactylia/genetics, Animal Disease Models, Animals, Brain/embryology, Craniosynostoses/genetics, Developmental Gene Expression Regulation, Fibroblast Growth Factor Receptor Type 2 /metabolism, Inbred C57BL Mice, Magnetic Resonance Spectroscopy, Mice, Mutation, Phenotype, Time Factors, Transgenic Mice, X-Ray Computed Tomography/methods