Tag Archives: Animal Disease Models

SSC-ILD mouse model induced by osmotic minipump delivered bleomycin: effect of Nintedanib

Francesca Ravanetti et al. SSC-ILD mouse model induced by osmotic minipump delivered bleomycin: effect of Nintedanib Scientific Reports. Publication Date September 16, 2021 How Analyze was Used “For each acquisition, a stack of 512 cross-sectional images was produced. The reconstructed datasets were analyzed using the Perkin Elmer Analyze software (Analyze 12.0; Copyright 1986–2017…). The images…

In-vivo lung fibrosis staging in a bleomycin-mouse model: a new micro-CT guided densitometric approach

Laura Mecozzi et al. In-vivo lung fibrosis staging in a bleomycin-mouse model: a new micro-CT guided densitometric approach Scientific Reports. Publication Date October 30, 2020 How Analyze was Used “For each acquisition, a stack of 512 cross-sectional images stored in unsigned 16-bit file format was produced. The reconstructed datasets were imported and analyzed using Analyze…

Sex differences in brain MRI abnormalities and neurodevelopmental outcomes in a rat model of neonatal hypoxia-ischemia

Huang HZ, Wen XH, Liu H. Sex differences in brain MRI abnormalities and neurodevelopmental outcomes in a rat model of neonatal hypoxia-ischemia. Int J Neurosci. August 2015:1-11. Publication Date August 2015 How Analyze was Used “Lesion size was measured from the acquired images using Analyze 5.0 software … Lesion volume was the sum of the…

Clinical correlates of raphe serotonergic dysfunction in early Parkinson’s disease

Qamhawi Z, Towey D, Shah B, Pagano G, Seibyl J, Marek K, Borghammer P, Brooks DJ, Pavese N. Clinical correlates of raphe serotonergic dysfunction in early Parkinson’s disease. Brain. July 2015. Publication Date July 2015 How Analyze was Used “Available images were loaded together with a single subject MRI template in Montreal Neurological Institute space…

In vivo MRI evidence that neuropathology is attenuated by cognitive enrichment in the YAC128 Huntington’s Disease mouse model

Steventon JJ, Harrison DJ, Trueman RC, Rosser AE, Jones DK, Brooks SP. In vivo MRI evidence that neuropathology is attenuated by cognitive enrichment in the YAC128 Huntington’s Disease mouse model. J Huntingtons Dis. July 2015;4(2):149-160. Publication Date July 2015 How Analyze was Used “Processing of the T 2 -weighted images was carried out using Analyze…

An athymic rat model for mandibular osteoradionecrosis allowing for direct translation of regenerative treatments

Jackson RS, Voss SG, Wilson ZC, Remmes NB, Stalboerger PG, Keeney MG, Moore EJ, Janus JR. An athymic rat model for mandibular osteoradionecrosis allowing for direct translation of regenerative treatments. Otolaryngol Head Neck Surg. July 2015. Publication Date July 2015 How Analyze was Used “The resulting 3-dimensional images consist of 20-µm cubic voxels and were…

Assessing the accuracy and reproducibility of modality independent elastography in a murine model of breast cancer

Weis JA, Flint KM, Sanchez V, Yankeelov TE, Miga MI. Assessing the accuracy and reproducibility of modality independent elastography in a murine model of breast cancer. J Med Imaging. July 2015;2(3):036001-036001. Full Text – Open Access Publication Date July 2015 How Analyze was Used “MR image volumes were semiautomatically processed to segment the object of…

Impact of short-term 1,25-dihydroxyvitamin D3 on the chemopreventive efficacy of erlotinib against oral cancer

Bothwell KD, Shaurova T, Merzianu M, Suresh A, Kuriakose MA, Johnson CS, Hershberger PA, Seshadri M. Impact of short-term 1,25-dihydroxyvitamin D3 on the chemopreventive efficacy of erlotinib against oral cancer. Cancer Prev Res (Phila). June 22015. Publication Date June 2015 How Analyze was Used “Following MR image acquisition, raw image sets were transferred to a…

Blocking stroke-induced immunodeficiency increases CNS antigen-specific autoreactivity but does not worsen functional outcome after experimental stroke

Römer C, Engel O, Winek K, Hochmeister S, Zhang T, Royl G, Klehmet J, Dirnagl U, Meisel C, Meisel A. Blocking stroke-induced immunodeficiency increases CNS antigen-specific autoreactivity but does not worsen functional outcome after experimental stroke. J Neurosci. May 2015;35(20):7777-7794. Publication Date May 2015 How Analyze was Used “Axial slices covered the distance between the…

Evaluation of 11C-Acetate and 18F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma

Territo PR, Maluccio M, Riley AA, McCarthy BP, Fletcher J, Tann M, Saxena R, Skill NJ. Evaluation of 11C-Acetate and 18F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma. BMC Med Imaging. May 2015;15(1):15. Full Text – Open Access Publication Date May 2015 How Analyze was Used “In all cases, CT…