AnalyzeDirect Territo PR, Maluccio M, Riley AA, McCarthy BP, Fletcher J, Tann M, Saxena R, Skill NJ. Evaluation of 11C-Acetate and 18F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma. BMC Med Imaging. May 2015;15(1):15.
Full Text – Open Access
Publication Date
May 2015
How Analyze was Used
“In all cases, CT images were co-registered to 18F-FDG and 11C-acetate PET image volumes using Analyze 11.0 (AnalyzeDirect) software based on the maximum entropy and mutual information algorithm described previously [Studholme et al. 1997]. Manual whole liver segmentation was performed on registered CT image volumes (Analyze 11.0, AnalyzeDirect).”
Keywords
Carbon-11 Acetate
Carcinoma, Hepatocellular
Contrast Media
Disease Models, Animal
Drug Evaluation, Preclinical
Drug Resistance, Multiple
Enzyme-Linked Immunosorbent Assay
Fluorodeoxyglucose F18
Genes, MDR
Humans
Liver Neoplasms
Mice
Positron Emission Tomography (PET)
Tomography, X-Ray Computed (CT)
Tumor Necrosis Factor-alpha
Author Affiliation(s)
Department of Surgery, Indiana University School of Medicine, C519 Walthur Cancer Research Building (R3), 980 W Walnut Street, Indianapolis 46077, IN, US. (MM, NJS)
Department of Surgery, Radiology and Imaging Sciences, Indianapolis 46202, IN, US. (PRT, AAR, BPM, JF, MT, RS)
ID# 2564
Tags: Animal Disease Models, Carbon-11 Acetate, Contrast Media, Enzyme-Linked Immunosorbent Assay, Fluorodeoxyglucose F18, Hepatocellular Carcinoma, Humans, Liver Neoplasms, MDR Genes, Mice, Multiple Drug Resistance, Positron Emission Tomography (PET), Preclinical Drug Evaluation, Tumor Necrosis Factor-alpha, X-Ray Computed Tomography (CT)