Analyze Publications Database

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

Yu T, Li Z, Jia Z, Clapcote SJ, Liu C, Li S, Asrar S, Pao A, Chen R, Fan N, Carattini-Rivera S, Bechard AR, Spring S, Henkelman RM, Stoica G, Matsui S, Nowak NJ, Roder JC, Chen C, Bradley A, Yu YE. A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions. Hum Mol Genet. July 2010;19(14):2780-2791.

Full Text – Open Access

Publication Date
July 2010

How Analyze was Used
“MR data analyses were carried out using Analyze PC (Version 7.0, AnalyzeDirect, Overland Park, KS, USA).”

Keywords
Animals
Cells, Cultured
Chromosomes, Human, Pair 21/genetics
Disease Models, Animal
Down Syndrome/genetics/pathology/physiopathology
Female
Hand Strength/physiology
Hippocampus/physiopathology
Humans
Male
Maze Learning/physiology
Mice
Mice, Inbred C57BL
Mice, Transgenic
Models, Biological
Physical Conditioning, Animal
Pregnancy
Synteny/genetics

Author Affiliation(s)
Genetics Program and Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (TY, ZL, CL, AP, SIM, NJN, YEY)

New York State Center of Excellence in Bioinformatics and Life Sciences, Buffalo, NY 14263, US. (NJN, YEY)

Department of Cellular and Molecular Biology, Roswell Park Division of Graduate School, State University of New York at Buffalo, Buffalo, NY 14263, US. (NJN, YEY)

Neurosciences and Mental Health Program, Hospital for Sick Children, Department of Physiology, University of Toronto, Toronto, ON, Canada M5G 1X8. (ZJ, SA)

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada M5G 1X5. (SJC, ARB, JCR)

Center for Neurologic Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, US. (SL)

Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112, US. (RC, NF, CC)

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, US. (SCR)

Department of Medical Biophysics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada M5S 1A1. (SS, RMH)

Department of Pathobiology, Texas A&M University, College Station, TX 77843, US. (GS)

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK. (AB)

ID# 1151

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