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Li G, Jack CR, Yang XF, Yang ES. Diet supplement CoQ10 delays brain atrophy in aged transgenic mice with mutations in the amyloid precursor protein: an in vivo volume MRI study. Biofactors. December 2008;32(1-4):169-178.

Publication Date
December 2008

How Analyze was Used
“The hemispheric and hippocampal volumes were delineated with manual region of interest (ROI) tracing using the image processing software Analyze 6.0 (AnalyzeDirect USA).”

Keywords
Aging/physiology
Animals
Antioxidants/therapeutic use
Atrophy/prevention & control
Brain/pathology
Cerebrum/anatomy & histology/drug effects
Cognition Disorders/prevention & control
Female
Free Radical Scavengers/therapeutic use
Hippocampus/anatomy & histology/drug effects
Magnetic Resonance Imaging/veterinary
Male
Mice
Mice, Transgenic
Presenilin-1/genetics
Serum Amyloid A Protein/genetics
Ubiquinone/analogs & derivatives/therapeutic use

Author Affiliation(s)
Hong Kong Applied Science and Technology Research Institute Company Limited, Hong Kong, HKSAR, China. (GL, XFY, ESY)

Department of Radiology, Mayo Clinic and Foundation, Rochester, MN, US. (CRJ)

ID# 1492

Tags: Aging/physiology, Animals, Antioxidants/therapeutic use, Atrophy/prevention & control, Brain/pathology, Cerebrum/anatomy & histology/drug effects, Cognition Disorders/prevention & control, Female, Free Radical Scavengers/therapeutic use, Hippocampus/anatomy & histology/drug effects, Magnetic Resonance Imaging (MRI)/veterinary, Male, Mice, Presenilin-1/genetics, Serum Amyloid A Protein/genetics, Transgenic Mice, Ubiquinone/analogs & derivatives/therapeutic use