Tag Archives: Osteoporosis

An antagonistic monoclonal anti–Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis

Melanie Vogler et al. An antagonistic monoclonal anti–Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis JOR Spine. Publication Date July 15, 2022 How Analyze was Used “Reconstructed volumes were loaded into Analyze14 software (AnalyzeDirect) for 3D segmentation of the bone structure by thresholds method. Group sizes had been designed…

Protection against Osteoporosis by Fermented Mulberry Vinegar Supplementation via Inhibiting Osteoclastic Activity in Ovariectomized Rats and Osteoclastic Cells

Eun Jung Yim et al. Protection against Osteoporosis by Fermented Mulberry Vinegar Supplementation via Inhibiting Osteoclastic Activity in Ovariectomized Rats and Osteoclastic Cells Fermentation. Publication Date May 5, 2022 How Analyze was Used “The femur was fixed with 4% paraformaldehyde, and its bone status was measured. Micro-CT imaging was performed using a Quantum GX Micro-CT…

Inhibition of RANKL-Induced Osteoclastogenesis by Novel Mutant RANKL

Yuria Jang et al. Inhibition of RANKL-Induced Osteoclastogenesis by Novel Mutant RANKL International Journal of Molecular Sciences. Publication Date January 6, 2021 How Analyze was Used “Micro-CT scanning for the distal femur was distally initiated at the level of the growth plate using a Quantum GX micro-CT imaging system (PerkinElmer, Hopkinton, MA, USA) located at…

OPG-Fc treatment partially rescues low bone mass phenotype in mature Bgn/Fmod deficient mice but is deleterious to the young mouse skeleton

Vardit Kram et al. OPG-Fc treatment partially rescues low bone mass phenotype in mature Bgn/Fmod deficient mice but is deleterious to the young mouse skeleton Journal of Structural Biology. Publication Date September 17, 2020 How Analyze was Used “Skull scans were exported to Analyze 14.0 software (AnalyzeDirect, KS, USA) for further analysis. All skulls were…

Modification of the RANKL-RANK-binding site for the immunotherapeutic treatment of osteoporosis

Y. Ko et al. Modification of the RANKL-RANK-binding site for the immunotherapeutic treatment of osteoporosis. Osteoporosis International. Publication Date December 20, 2019 How Analyze was Used “The resolution was set at 4.5 μm and images were obtained. Following scanning, the structural parameters for trabecular bone were analyzed with Analyze 12.0 software (AnalyzeDirect, Overland Park, KS,…

Methoxsalen supplementation attenuates bone loss and inflammatory response in ovariectomized mice

Ju Ri Ham et al. Methoxsalen supplementation attenuates bone loss and inflammatory response in ovariectomized mice. Chemico-Biological Interactions. October 23, 2017. Publication Date October 2017 How Analyze was Used “The structural parameters for trabecular bone were analyzed using Analyze 12.0 (AnalyzeDirect, Inc., Overland Park, KS, USA). BMD, bone surface (BS), bone surface density (BS/TV), total…

Excessive Vitamin E Intake Does Not Cause Bone Loss in Male or Ovariectomized Female Mice Fed Normal or High-Fat Diets

Hiroko Ikegami, Rie Kawawa, Ikuyo Ichi, Tomoko Ishikawa, Taisuke Koike, Yoshinori Aoki, Yoko Fujiwara. Excessive Vitamin E Intake Does Not Cause Bone Loss in Male or Ovariectomized Female Mice Fed Normal or High-Fat Diets. The Journal of Nutrition. August 23, 2017. Publication Date August 2017 How Analyze was Used “After scanning, 3-dimensional bone parameters were…

Fatigue microcracks that initiate fracture are located near elevated intracortical porosity but not elevated mineralization

Turnbull TL, Baumann AP, Roeder RK. Fatigue microcracks that initiate fracture are located near elevated intracortical porosity but not elevated mineralization. J Biomech. June 2014. Publication Date June 2014 How Analyze was Used “The gauge section was segmented to reveal labeled microdamage (DV), which was overlaid on micro-CT images of the as-prepared specimens using image…

Differences of bone healing in metaphyseal defect fractures between osteoporotic and physiological bone in rats

Thormann U, El Khawassna T, Ray S, Duerselen L, Kampschulte M, Lips K, von Dewitz H, Heinemann S, Heiss C, Szalay G, Langheinrich AC, Ignatius A, Schnettler R, Alt V. Differences of bone healing in metaphyseal defect fractures between osteoporotic and physiological bone in rats. Injury. March 2014;45(3):487-493. Full Text – Open Access Publication Date…

Isolation and characterization of human osteoblasts from needle biopsies without in vitro culture

Fujita K, Roforth MM, Atkinson EJ, Peterson JM, Drake MT, McCready LK, Farr JN, Monroe DG, Khosla S. Isolation and characterization of human osteoblasts from needle biopsies without in vitro culture. Osteoporos Int. March 2014;25(3):887-895. Publication Date March 2014 How Analyze was Used “The entire length of the bone biopsies was scanned by placing them…