Tag Archives: Osteoporosis

Mechanical Analysis of Romosozumab’s Effects on Bone Strength in a Rat Posterolateral Lumbar Fusion Model

Tomohito Mukaihata et al. Mechanical Analysis of Romosozumab’s Effects on Bone Strength in a Rat Posterolateral Lumbar Fusion Model Springer Nature: Cureus Publication Date February 27, 2025 How Analyze was Used “In addition, to qualitatively evaluate bone fusion, the volume of fused bone in both groups was measured and compared using Analyze 12 software (AnalyzeDirect,…

Bifidobacterium longum increases serum vitamin D metabolite levels and modulates intestinal flora to alleviate osteoporosis in mice

Hongchao Wang et al. Bifidobacterium longum increases serum vitamin D metabolite levels and modulates intestinal flora to alleviate osteoporosis in mice Food Microbiology Publication Date February 21, 2025 How Analyze was Used “Each femur was meticulously rotated a full circle to ensure comprehensive data capture, which was subsequently transferred to Analyze software version 12.0 by…

Denatonium inhibits RANKL-induced osteoclast differentiation and rescues the osteoporotic phenotype by blocking p65 signaling pathway

Sheunghun Lee et al. Denatonium inhibits RANKL-induced osteoclast differentiation and rescues the osteoporotic phenotype by blocking p65 signaling pathway Molecular Medicine. Publication Date December 19, 2024 How Analyze was Used “For micro-CT analysis, trabecular bone parameters were analyzed by Analyze 12.0 software (AnalyzeDirect, KS, USA), and the distal femur was scanned using a Quantum GX…

Effects of elastase-induced emphysema on muscle and bone in mice

Daichi Matsumura et al. Effects of elastase-induced emphysema on muscle and bone in mice PLOS One. Publication Date June 23, 2023 How Analyze was Used “The microstructural parameters of the femur were assessed using the visualization and analysis software, Analyze 14.0 (AnalyzeDirect, Inc., KS, USA). A 1-mm-thick region from 100 μm proximal to the end…

Loss of MGAT5 is involved in the impaired osteogenic differentiation of bone marrow mesenchymal stem cells

Xiao-Po Liu et al. Loss of MGAT5 is involved in the impaired osteogenic differentiation of bone marrow mesenchymal stem cells Experimental Animals. Publication Date April 5, 2023 How Analyze was Used “Femur samples were scanned with Quantum GX micro-CT system (PerkinElmer, Massachusetts, USA) at a voxel size of 10 μm. Quantum and Caliper Analyze software…

Moringa oleifera leaf attenuate osteoporosis in ovariectomized rats by modulating gut microbiota composition and MAPK signaling pathway

Xue-Hong Hu et al. Moringa oleifera leaf attenuate osteoporosis in ovariectomized rats by modulating gut microbiota composition and MAPK signaling pathway Biomedicine & Pharmacotherapy. Publication Date February 23, 2023 How Analyze was Used “The right femurs were analyzed by microCT (PerkinElmer Quantum GX micro CT Imaging System; PerkinElmer, Billerica, MA, USA). Datasets were reconstructed using…

Protective effects of the postbiotic Lactobacillus plantarum MD35 on bone loss in an ovariectomized mice model

Ju-Yeong Myeong et al. Protective effects of the postbiotic Lactobacillus plantarum MD35 on bone loss in an ovariectomized mice model ResearchSquare. Publication Date October 21, 2022 How Analyze was Used “The structural parameters for trabecular bone were analyzed using Analyze software (version 12.0; AnalyzeDirect, Overland Park, KS, USA). Bone mineral density of the femur was…

An antagonistic monoclonal anti–Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis

Melanie Vogler et al. An antagonistic monoclonal anti–Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis JOR Spine. Publication Date July 15, 2022 How Analyze was Used “Reconstructed volumes were loaded into Analyze14 software (AnalyzeDirect) for 3D segmentation of the bone structure by thresholds method. Group sizes had been designed…

Protection against Osteoporosis by Fermented Mulberry Vinegar Supplementation via Inhibiting Osteoclastic Activity in Ovariectomized Rats and Osteoclastic Cells

Eun Jung Yim et al. Protection against Osteoporosis by Fermented Mulberry Vinegar Supplementation via Inhibiting Osteoclastic Activity in Ovariectomized Rats and Osteoclastic Cells Fermentation. Publication Date May 5, 2022 How Analyze was Used “The femur was fixed with 4% paraformaldehyde, and its bone status was measured. Micro-CT imaging was performed using a Quantum GX Micro-CT…

Inhibition of RANKL-Induced Osteoclastogenesis by Novel Mutant RANKL

Yuria Jang et al. Inhibition of RANKL-Induced Osteoclastogenesis by Novel Mutant RANKL International Journal of Molecular Sciences. Publication Date January 6, 2021 How Analyze was Used “Micro-CT scanning for the distal femur was distally initiated at the level of the growth plate using a Quantum GX micro-CT imaging system (PerkinElmer, Hopkinton, MA, USA) located at…