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Bifidobacterium longum increases serum vitamin D metabolite levels and modulates intestinal flora to alleviate osteoporosis in mice

Hongchao Wang et al. Bifidobacterium longum increases serum vitamin D metabolite levels and modulates intestinal flora to alleviate osteoporosis in mice Food Microbiology

Publication Date
February 21, 2025

How Analyze was Used
“Each femur was meticulously rotated a full circle to ensure comprehensive data capture, which was subsequently transferred to Analyze software version 12.0 by AnalyzeDirect for three-dimensional (3D) modeling and evaluation. The analysis focused on a region of interest (ROI) extending 1 mm in thickness, commencing 0.2 mm beneath the growth plate, to ascertain various bone metrics. The pivotal parameters measured encompassed the average bone density (BM), average cortical density (CM), average trabecular density (TM), spacing between trabeculae (Tb.Sp), count of trabeculae (Tb.N), thickness of trabeculae (Tb.Th), surface area of the bone (BS), total bone volume (BV), ratio of bone volume to total volume (BV/TV), and density of bone trabecular connectivity (Conn.D).”

Keywords
Osteoporosis, Gut microbiota, Vitamin D, Active vitamins

Author Affiliation(s)
Jiangnan University, Wuxi, Jiangsu, China

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