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Protective effects of the postbiotic Lactobacillus plantarum MD35 on bone loss in an ovariectomized mice model

Ju-Yeong Myeong et al. Protective effects of the postbiotic Lactobacillus plantarum MD35 on bone loss in an ovariectomized mice model ResearchSquare.

Publication Date
October 21, 2022

How Analyze was Used
“The structural parameters for trabecular bone were analyzed using Analyze software (version 12.0; AnalyzeDirect, Overland Park, KS, USA). Bone mineral density of the femur was estimated using a hydroxyapatite (HA) phantom (QRM-MicroCT-HA, Quality Assurance in Radiology and Medicine GmbH, Germany) and scanned using the same parameters. Bone mineral density (BMD), bone volume (BV), bone volume fraction (BV/TV), trabecular thickness (Tb.Th), trabecular separation (Tb.Sp), and trabecular number (Tb.N) were calculated using ROI. For the growth plate measurement, the growth plate region was outlined and selected in the 2D and 3D growth plate slices, which were rendered into an area and volume for calculations.”

Keywords
Lactobacillus plantarum, Postbiotics, Osteoclast, Osteoporosis

Author Affiliation(s)
Korea Basic Science Institute, Daejeon, South Korea

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