Daichi Matsumura et al. Effects of elastase-induced emphysema on muscle and bone in mice PLOS One.
Publication Date
June 23, 2023
How Analyze was Used
“The microstructural parameters of the femur were assessed using the visualization and analysis software, Analyze 14.0 (AnalyzeDirect, Inc., KS, USA). A 1-mm-thick region from 100 μm proximal to the end of the growth plate was used in the trabecular bone analysis, and the following parameters were assessed: trabecular bone volume fraction (BV/TV), trabecular BMD, trabecular number (Tb.N), trabecular thickness (Tb.Th), trabecular separation (Tb.Sp) and connectivity density (Conn.D). A 1-mm-thick region of the mid-diaphysis of the femur was used in the cortical bone analysis, and the following parameters were assessed: cortical BMD, cortical thickness (Ct.Th) and cortical area (Ct.Ar).”
Keywords
Emphysema, Muscle loss, Bone loss, Mice, Chronic obstructive pulmonary disease (COPD), Sarcopenia, Osteoporosis
Author Affiliation(s)
Kindai University, Osaka, Japan