Tag Archives: Aging

Metabolic effects of testosterone added to intensive lifestyle intervention in older men with obesity and hypogonadism

Adrian M Gonzalez-Gil et al. Metabolic effects of testosterone added to intensive lifestyle intervention in older men with obesity and hypogonadism The Journal of Clinical Endocrinology & Metabolism. Publication Date April 12, 2024 How Analyze was Used “Baseline and 6-month images were batched and analyzed using AnalyzeDirect software (version 12.0; Mayo Clinic, Rochester, MN), which…

Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice

Bibi S. van Thiel et al. Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice Molecular Imaging and Biology. Publication Date March 18, 2024 How Analyze was Used “Indexes of LV myocardial mass (LVMM) and LV function (LV end-diastolic volume, LV end-systolic volume and LV stroke volume)…

Gastric inhibitory polypeptide receptor antagonism suppresses intramuscular adipose tissue accumulation and ameliorates sarcopenia

Yuya Takahashi et al. Gastric inhibitory polypeptide receptor antagonism suppresses intramuscular adipose tissue accumulation and ameliorates sarcopenia Journal of Cachexia, Sarcopenia and Muscle. Publication Date October 27, 2023 How Analyze was Used “Contiguous slice images of the whole body were used for quantitative assessment using Analyze 12.0 (AnalyzeDirect, Overland Park, KS, USA). Weights of bone,…

Deciphering the decline of metabolic elasticity in aging and obesity

Qiuzhong Zhou et al. Deciphering the decline of metabolic elasticity in aging and obesity Cell Metabolism. Publication Date August 24, 2023 How Analyze was Used “The bones were then stained for 48 hours in 1% osmium tetroxide, 2.5% potassium dichromate solution at RT, washed in tap water for at least 2 hours, and imaged by…

Resurrection of endogenous retroviruses during aging reinforces senescence

Xiaoqian Liu et al. Resurrection of endogenous retroviruses during aging reinforces senescence Cell. Publication Date January 6, 2023 How Analyze was Used “The Micro-Computed Tomography (Micro-CT) scanning was conducted using a PE Quantum FX (PerkinElmer) on living mice. Briefly, the mice were anesthetized with isoflurane and scanned using the following settings. The proximal part of…

Topological reorganization of brain network might contribute to the resilience of cognitive functioning in mildly disabled relapsing remitting multiple sclerosis

Arzu Ceylan Has Silemek et al. Topological reorganization of brain network might contribute to the resilience of cognitive functioning in mildly disabled relapsing remitting multiple sclerosis Journal of Neuroscience Research. Publication Date October 19, 2022 How Analyze was Used “Lesion intensities were specified semi-automatically by Analyze 11.0 software (AnalyzeDirect, www.analyzedirect.com). Then, lesion filling was done…

Weight loss and exercise differentially affect insulin sensitivity, body composition, cardiorespiratory fitness and muscle strength in older adults with obesity; a randomized controlled trial

Andrea M Brennan et al. Weight loss and exercise differentially affect insulin sensitivity, body composition, cardiorespiratory fitness and muscle strength in older adults with obesity; a randomized controlled trial The Journals of Gerontology: Series A. Publication Date August 18, 2021 How Analyze was Used “Resultant images were analyzed and segmented using Analyze 11.0 (Biomedical Imaging…

Testosterone Replacement Therapy added to Intensive Lifestyle Intervention in Older Men with Obesity and Hypogonadism

Yoann Barnouin et al. Testosterone Replacement Therapy added to Intensive Lifestyle Intervention in Older Men with Obesity and Hypogonadism The Journal of Clinical Endocrinology & Metabolism. Publication Date December 22, 2020 How Analyze was Used “Muscle and fat volumes were quantified in each slice by Analyze Direct software (version 10.0).” Keywords Testosterone, Obesity, Aging, Diet,…

Older adults with sarcopenia have distinct skeletal muscle phosphodiester, phosphocreatine, and phospholipid profiles

James Matthew Hinkley et al. Older adults with sarcopenia have distinct skeletal muscle phosphodiester, phosphocreatine, and phospholipid profiles. Aging Cell. Publication Date May 28, 2020 How Analyze was Used “Additionally, thigh muscle composition was determined by MRI using a 3T Philips Achieva magnet as previously described. Muscle volume was determined by Analyze 11.0 software.” Keywords…

Population-based study of age- and sex-related differences in muscle density and size in thoracic and lumbar spine: the Framingham study

F. Johannesdottir et al. Population-based study of age- and sex-related differences in muscle density and size in thoracic and lumbar spine: the Framingham study. Osteoporosis International. Publication Date March 22 2018 How Analyze was Used “Each CT scan was spatially filtered using a sigma filter to reduce noise, and each muscle was contoured at the…