AnalyzeDirect Bibi S. van Thiel et al. Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice Molecular Imaging and Biology.
Publication Date
March 18, 2024
How Analyze was Used
“Indexes of LV myocardial mass (LVMM) and LV function (LV end-diastolic volume, LV end-systolic volume and LV stroke volume) were measured from the 3D micro-CT images using the software ANALYZE ® 12.0 (AnalyzeDirect Inc., Overland Parks, KS, USA). Subsequently, stroke volume was calculated as LV-end-diastolic volume – LV end-systolic volume, while LV ejection fraction was calculated using this formula: ((LV end-diastolic volume-LV end-systolic volume)/LV end-diastolic volume)*100%.”
Keywords
Molecular imaging, Aging, Heart failure, DNA repair, Ercc1, FMT, CT
Author Affiliation(s)
Erasmus University Medical Center, Rotterdam, The Netherlands
