Kurenova E, Liao J, He DH, Hunt D, Yemma M, Bshara W, Seshadri M, Cance WG. The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth. Oncotarget. October 2013;4(10):1632-1646. Full Text – Open Access Publication Date October 2013 How Analyze was Used “Image processing and analysis were carried out using commercially available…
Francescutti V, Rivera L, Seshadri M, Kim M, Haslinger M, Camoriano M, Attwood K, Kane JM, 3rd, Skitzki JJ. The benefit of intraperitoneal chemotherapy for the treatment of colorectal carcinomatosis. Oncol Rep. July 2013;30(1):35-42. Full Text – Open Access Publication Date July 2013 How Analyze was Used “Post processing of datasets was performed using the…
Ma Y, Yu WD, Su B, Seshadri M, Luo W, Trump DL, Johnson CS. Regulation of motility, invasion, and metastatic potential of squamous cell carcinoma by 1alpha,25-dihydroxycholecalciferol. Cancer. July 2013;119(3):563-574. Full Text – Open Access Publication Date July 2013 How Analyze was Used “After image acquisition, raw image sets were transferred to a processing workstation…
Lee S, Wurtzel JGT, Singhal SS, Awasthi S, Goldfinger LE. RALBP1/RLIP76 depletion in mice suppresses tumor growth by inhibiting tumor neovascularization. Cancer Res. October 2012;72(20):5165-5173. Full Text – Open Access Publication Date October 2012 How Analyze was Used “Samples were positioned on a computer-controlled rotation stage and scanned 180° around the vertical axis in rotation…
Simmons BH, Lee JH, Lalwani K, Giddabasappa A, Snider BA, Wong A, Lappin PB, Eswaraka J, Kan JL, Christensen JG, Shojaei F. Combination of a MEK inhibitor at sub-MTD with a PI3K/mTOR inhibitor significantly suppresses growth of lung adenocarcinoma tumors in Kras(G12D-LSL) mice. Cancer Chemother Pharmacol. August 2012;70(2):213-220. Full Text – Open Access Publication Date…
Ellis L, Shah P, Hammers H, Lehet K, Sotomayor P, Azabdaftari G, Seshadri M, Pili R. Vascular disruption in combination with mTOR inhibition in renal cell carcinoma. Mol Cancer Ther. February 2012;11(2):383-392. Full Text – Open Access Publication Date February 2012 How Analyze was Used “Image processing and analysis were carried out using commercially available…
Lee EC, Fitzgerald M, Bannerman B, Donelan J, Bano K, Terkelsen J, Bradley DP, Subakan O, Silva MD, Liu R, Pickard M, Li Z, Tayber O, Li P, Hales P, Carsillo M, Neppalli VT, Berger AJ, Kupperman E, Manfredi M, Bolen JB, Van Ness B, Janz S. Antitumor activity of the investigational proteasome inhibitor MLN9708…
Cao S, Durrani FA, Toth K, Rustum YM, Seshadri M. Bevacizumab enhances the therapeutic efficacy of Irinotecan against human head and neck squamous cell carcinoma xenografts. Oral Oncol. June 2011;47(6):459-466. Full Text – Open Access Publication Date June 2011 How Analyze was Used “All post processing and analysis were performed using Analyze™ (AnalyzeDirect, Overland Park,…
Seidel K, Kirsch S, Lucht K, Zaade D, Reinemund J, Schmitz J, Klare S, Li Y, Schefe JH, Schmerbach K, Goldin-Lang P, Zollmann FS, Thone-Reineke C, Unger T, Funke-Kaiser H. The promyelocytic leukemia zinc finger (PLZF) protein exerts neuroprotective effects in neuronal cells and is dysregulated in experimental stroke. Brain Pathol. January 2011;21(1):31-43. Publication Date…
Dinca EB, Voicu RV, Ciurea AV. Bioluminescence imaging of invasive intracranial xenografts: implications for translational research and targeted therapeutics of brain tumors. Neurosurg Rev. October 2010;33(4):385-394. Publication Date October 2010 How Analyze was Used “In addition to studies correlating two imaging modalities (BLI and MRI), an alternative validation approach also found an outstanding correspondence (r2…