AnalyzeDirect Dinca EB, Voicu RV, Ciurea AV. Bioluminescence imaging of invasive intracranial xenografts: implications for translational research and targeted therapeutics of brain tumors. Neurosurg Rev. October 2010;33(4):385-394.
Publication Date
October 2010
How Analyze was Used
“In addition to studies correlating two imaging modalities (BLI and MRI), an alternative validation approach also found an outstanding correspondence (r2 higher than 0.9) between BLI measurements of supratentorial tumors in nude mice … or brainstem tumors in nude rats … and the actual tumor volume, as measured by sophisticated histopathologic morphometry using the Analyze 7.0 software.”
Keywords
Animals
Animals, Genetically Modified
Antineoplastic Agents/therapeutic use
Brain Neoplasms/drug therapy/pathology
Cell Line, Tumor
Humans
Kaplan-Meier Estimate
Luminescence
Mice
Mice, Nude
Neoplasm Transplantation/pathology
Neoplasms, Experimental/drug therapy/pathology
Translational Medical Research
Transplantation, Heterologous
Author Affiliation(s)
Department of Neurosurgery, “Bagdasar-Arseni” Hospital, Sos. Berceni nr. 12, sector 4, 041915, Bucharest, Romania. (EBD, AVC)
Department of Neurosurgery, University of California, San Francisco, CA, US. (RVV)
ID# 1065
Tags: Animals, Antineoplastic Agents/therapeutic use, Brain Neoplasms/drug therapy/pathology, Experimental Neoplasms/drug therapy/pathology, Genetically Modified Animals, Heterologous Transplantation, Humans, Kaplan-Meier Estimate, Luminescence, Mice, Neoplasm Transplantation/pathology, Nude Mice, Translational Medical Research, Tumor Cell Line