Tag Archives: Gene Expression/drug effects

Effects of aliskiren on stroke in rats expressing human renin and angiotensinogen genes

Schmerbach K, Pfab T, Zhao Y, Culman J, Mueller S, Villringer A, Muller DN, Hocher B, Unger T, Thoene-Reineke C. Effects of aliskiren on stroke in rats expressing human renin and angiotensinogen genes. PLoS One. November 2010;5(11):e15052. Full Text – Open Access Publication Date November 2010 How Analyze was Used “Calculation of lesion volume was…

Intradiscal injection of simvastatin retards progression of intervertebral disc degeneration induced by stab injury

Zhang H, Wang L, Park JB, Park P, Yang VC, Hollister SJ, La Marca F, Lin CY. Intradiscal injection of simvastatin retards progression of intervertebral disc degeneration induced by stab injury. Arthritis Res Ther. November 2009;11(6):R172. Full Text – Open Access Publication Date November 2009 How Analyze was Used “A procedure described previously was followed…

Comparison between single and combined treatment with candesartan and pioglitazone following transient focal ischemia in rat brain

Schmerbach K, Schefe JH, Krikov M, Müller S, Villringer A, Kintscher U, Unger T, Thoene-Reineke C. Comparison between single and combined treatment with candesartan and pioglitazone following transient focal ischemia in rat brain. Brain Res. May 2008;1208:225-233. Publication Date May 2008 How Analyze was Used “Calculation of lesion volume was carried out with the program…

PPARδ activation normalizes cardiac substrate metabolism and reduces right ventricular hypertrophy in congestive heart failure

Jucker BM, Doe CP, Schnackenberg CG, Olzinski AR, Maniscalco K, Williams C, Hu TC, Lenhard SC, Costell M, Bernard R, Sarov-Blat L, Steplewski K, Willette RN. PPARδ activation normalizes cardiac substrate metabolism and reduces right ventricular hypertrophy in congestive heart failure. J Cardiovasc Pharmacol. July 2007;50(1):25-34. Publication Date July 2007 How Analyze was Used “The…

Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy

Chaparro J, Reeds DN, Wen W, Xueping E, Klein S, Semenkovich CF, Bae KT, Quirk EK, Powderly WG, Yarasheski KE, Li E. Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy. Metabolism. May 2005;54(5):561-567. Full Text – Open Access Publication Date May 2005 How Analyze was Used “AnalyzeDirect software…

Fenfluramine evokes 5-HT2A receptor-mediated responses but does not displace [11C]MDL 100907: small animal PET and gene expression studies

Hirani E, Sharp T, Sprakes M, Grasby P, Hume S. Fenfluramine evokes 5-HT2A receptor-mediated responses but does not displace [11C]MDL 100907: small animal PET and gene expression studies. Synapse. December 2003;50(3):251-260. Publication Date December 2003 How Analyze was Used “Data were transferred into ANALYZE-AVW imaging software (Robb, 2001) and a standard VOI template, drawn from…