Tag Archives: Animals

The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth

Kurenova E, Liao J, He DH, Hunt D, Yemma M, Bshara W, Seshadri M, Cance WG. The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth. Oncotarget. October 2013;4(10):1632-1646. Full Text – Open Access Publication Date October 2013 How Analyze was Used “Image processing and analysis were carried out using commercially available…

Angiotensin receptor blockade has protective effects on the poststenotic porcine kidney

Zhang X, Eirin A, Li ZL, Crane JA, Krier JD, Ebrahimi B, Pawar AS, Zhu XY, Tang H, Jordan KL, Lerman A, Textor SC, Lerman LO. Angiotensin receptor blockade has protective effects on the poststenotic porcine kidney. Kidney Int. October 2013;84(4):767-775. Full Text – Open Access Publication Date October 2013 How Analyze was Used “160…

AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis

Bonnet CS, Williams AS, Gilbert SJ, Harvey AK, Evans BA, Mason DJ. AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis. Ann Rheum Dis. October 2013. Full Text – Open Access Publication Date October 2013 How Analyze was Used “For MRI, both knees (six AIA, six AIA+NBQX) were…

Improved visualization of neuronal injury following glial activation by manganese enhanced MRI

Bade AN, Zhou B, Epstein AA, Gorantla S, Poluektova LY, Luo J, Gendelman HE, Boska MD, Liu Y. Improved visualization of neuronal injury following glial activation by manganese enhanced MRI. J Neuroimmune Pharmacol. September 2013;8(4):1027-1036. Full Text – Open Access Publication Date September 2013 How Analyze was Used “The brain was…manually aligned to the LONI…

Redox signaling is an early event in the pathogenesis of renovascular hypertension

Hartono SP, Knudsen BE, Zubair AS, Nath KA, Textor SJ, Lerman LO, Grande JP. Redox signaling is an early event in the pathogenesis of renovascular hypertension. Int J Mol Sci. September 2013;14(9):18640-18656. Full Text – Open Access Publication Date September 2013 How Analyze was Used “The kidneys were removed, immersed in 10% formalin, and embedded…

Quantitative receptor-based imaging of tumor proliferation with the sigma-2 ligand [(18)F]ISO-1

Shoghi KI, Xu J, Su Y, He J, Rowland D, Yan Y, Garbow JR, Tu Z, Jones LA, Higashikubo R, Wheeler KT, Lubet RA, Mach RH, You M. Quantitative receptor-based imaging of tumor proliferation with the sigma-2 ligand [(18)F]ISO-1. PLoS One. September 2013;8(9):e74188. Full Text – Open Access Publication Date September 2013 How Analyze was…

Numerical metrics for automated quantification of interstitial cell of Cajal network structural properties

Gao J, Du P, O’Grady G, Archer R, Farrugia G, Gibbons SJ, Cheng LK. Numerical metrics for automated quantification of interstitial cell of Cajal network structural properties. J R Soc Interface. September 2013;10(86):20130421. Full Text – Open Access Publication Date September 2013 How Analyze was Used “Confocal image slices were sequentially taken throughout the transmural…

Reconstruction of critical-size mandibular defects in immunoincompetent rats with human adipose-derived stromal cells

Streckbein P, Jäckel S, Malik CY, Obert M, Kähling C, Wilbrand JF, Zahner D, Heidinger K, Kampschulte M, Pons-Kühnemann J, Köhler K, Sauer H, Kramer M, Howaldt HP. Reconstruction of critical-size mandibular defects in immunoincompetent rats with human adipose-derived stromal cells. J Craniomaxillofac Surg. September 2013;41(6):496-503. Publication Date September 2013 How Analyze was Used “The…cross-sectional…

Mouse brain fixation to preserve in vivo manganese enhancement for ex vivo manganese-enhanced MRI

Liu Y, Sajja BR, Gendelman HE, Boska MD. Mouse brain fixation to preserve In vivo manganese enhancement for ex vivo manganese-enhanced MRI. J Magn Reson Imaging. August 2013;38(2):482-487. Full Text – Open Access Publication Date August 2013 How Analyze was Used “Based on Paxinos mouse brain atlas [Paxinos and Franklin 2001], brain structures including cerebral cortex…

Changes in CT angiographic opacification of porcine coronary artery wall with patchy altered flow in vasa vasorum

Moritz R, Anderson JL, Vercnocke AJ, Wentz RJ, Ritman EL. Changes in CT angiographic opacification of porcine coronary artery wall with patchy altered flow in vasa vasorum. Int J Cardiovasc Imaging. August 2013;29(6):1325-1333. Full Text – Open Access Publication Date August 2013 How Analyze was Used “The resulting stack of transaxial tomographic images was displayed…