AnalyzeDirect Yang J, Wadghiri YZ, Hoang DM, Tsui W, Sun Y, Chung E, Li Y, Wang A, de Leon M, Wisniewski T. Detection of amyloid plaques targeted by USPIO-Aß1-42 in Alzheimer’s disease transgenic mice using magnetic resonance microimaging. Neuroimage. April 2011;55(4):1600-1609.
Full Text – Open Access
Publication Date
April 2011
How Analyze was Used
“The advantage of the 3D-imaging approach is that the image set can be reprocessed in any desired slice orientation using Analyze software (AnalyzeDirect, Overland Park, KS), facilitating image comparison during co-registration with histology.”
Keywords
Alzheimer Disease/complications/diagnosis
Amyloid beta-Peptides/diagnostic use
Animals
Contrast Media
Dextrans/diagnostic use
Drug Delivery Systems/methods
Magnetic Resonance Imaging (MRI)/methods
Magnetite Nanoparticles/diagnostic use
Mice
Mice, Inbred C57BL
Mice, Transgenic
Peptide Fragments/diagnostic use
Plaque, Amyloid/complications/diagnosis
Reproducibility of Results
Sensitivity and Specificity
Author Affiliation(s)
Department of Neurology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, US. (JY, YS, EC, YL, TW)
Department of Radiology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, US. (YZW, DMH)
Department of Psychiatry, New York University School of Medicine, 550 First Avenue, New York, NY 10016, US. (WT, ML, TW)
Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, US. (TW)
Nathan Kline Institute, Orangeburg, NY 10962, US. (ML)
Ocean NanoTech, LLC, 2143 Worth Lane, Springdale, AR 72764, US. (AW)
ID# 808
Tags: Alzheimer Disease/complications/diagnosis, Amyloid beta-Peptides/diagnostic use, Amyloid Plaque/complications/diagnosis, Animals, Contrast Media, Dextrans/diagnostic use, Drug Delivery Systems/methods, Inbred C57BL Mice, Magnetic Resonance Imaging (MRI)/methods, Magnetite Nanoparticles/diagnostic use, Mice, Peptide Fragments/diagnostic use, Reproducibility of Results, Sensitivity and Specificity, Transgenic Mice