Tag Archives: Nude Mice

Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor: insights from imaging

O’Connor JPB, Carano RAD, Clamp AR, Ross J, Ho CCK, Jackson A, Parker GJM, Rose CJ, Peale FV, Friesenhahn M, Mitchell CL, Watson Y, Roberts C, Hope L, Cheung S, Reslan HB, Go MAT, Pacheco GJ, Wu X, Cao TC, Ross S, Buonaccorsi GA, Davies K, Hasan J, Thornton P, del Puerto O, Ferrara N,…

[18F]fluoromethyl-[1,2-2H4]-choline: a novel radiotracer for imaging choline metabolism in tumors by positron emission tomography

Leyton J, Smith G, Zhao Y, Perumal M, Nguyen QD, Robins E, Arstad E, Aboagye EO. [18F]fluoromethyl-[1,2-2H4]-choline: a novel radiotracer for imaging choline metabolism in tumors by positron emission tomography. Cancer Res. October 2009;69(19):7721-7728. Full Text – Open Access Publication Date October 2009 How Analyze was Used “The image data sets were visualized using the…

MRI-based characterization of vascular disruption by 5,6-dimethylxanthenone-acetic acid in gliomas

Seshadri M, Ciesielski MJ. MRI-based characterization of vascular disruption by 5,6-dimethylxanthenone-acetic acid in gliomas. J Cereb Blood Flow Metab. August 2009;29(8):1373-1382. Full Text – Open Access Publication Date August 2009 How Analyze was Used “After image acquisition, raw image sets were transferred to a processing workstation and converted into Analyze format (AnalyzeDirect, Version 8.0, Overland…

Cooperation of the agonistic DR5 antibody apomab with chemotherapy to inhibit orthotopic lung tumor growth and improve survival

Jin H, Yang R, Ross J, Fong S, Carano R, Totpal K, Lawrence D, Zheng Z, Koeppen H, Stern H, Schwall R, Ashkenazi A. Cooperation of the agonistic DR5 antibody apomab with chemotherapy to inhibit orthotopic lung tumor growth and improve survival. Clin Cancer Res. December 2008;14(23):7733-7740. Full Text – Open Access Publication Date December…

Quantification of viable tumor microvascular characteristics by multispectral analysis

Berry LR, Barck KH, Go MA, Ross J, Wu X, Williams SP, Gogineni A, Cole MJ, Van Bruggen N, Fuh G, Peale F, Ferrara N, Ross S, Schwall RH, Carano RAD. Quantification of viable tumor microvascular characteristics by multispectral analysis. Magn Reson Med. July 2008;60(1):64-72. Publication Date July 2008 How Analyze was Used “A ‘brightfield’…

Tumor vascular maturation and improved drug delivery induced by methylselenocysteine leads to therapeutic synergy with anticancer drugs

Bhattacharya A, Seshadri M, Oven SD, Tόth K, Vaughan MM, Rustum YM. Tumor vascular maturation and improved drug delivery induced by methylselenocysteine leads to therapeutic synergy with anticancer drugs. Clin Cancer Res. June 2008;14(12):3926-3932. Full Text – Open Access Publication Date June 2008 How Analyze was Used “For determination of vessel lumen area, photomicrographs of…

3D micro-CT imaging of the postmortem brain

de Crespigny A, Bou-Reslan H, Nishimura MC, Phillips H, Carano RA, D’Arceuil HE. 3D micro-CT imaging of the postmortem brain. J Neurosci Methods. June 2008;171(2):207-213. Full Text – Open Access Publication Date June 2008 How Analyze was Used “Tumor borders were manually traced on all brains using Analyze software (AnalyzeDirect Inc., Lenexa, KS, USA) to…

Performance of a novel piezoelectric motor at 4.7 T: applications and initial tests

Turowski SG, Seshadri M, Loecher M, Podniesinski E, Spernyak JA, Mazurchuk RV. Performance of a novel piezoelectric motor at 4.7 T: applications and initial tests. Magn Reson Imaging. April 2008;26(3):426-432. Publication Date April 2008 How Analyze was Used “Image processing and analysis of all raw data sets were carried out using commercially available software (ANALYZE…

Blocking vascular endothelial growth factor-A inhibits the growth of pituitary adenomas and lowers serum prolactin level in a mouse model of multiple endocrine neoplasia type 1

Korsisaari N, Ross J, Wu X, Kowanetz M, Pal N, Hall L, Eastham-Anderson J, Forrest WF, Van Bruggen N, Peale FV, Ferrara N. Blocking vascular endothelial growth factor-A inhibits the growth of pituitary adenomas and lowers serum prolactin level in a mouse model of multiple endocrine neoplasia type 1. Clin Cancer Res. January 2008;14(1):249-258. Full…

Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models

Desnoyers LR, Pai R, Ferrando RE, Hötzel K, Le T, Ross J, Carano R, D’Souza A, Qing J, Mohtashemi I, Ashkenazi A, French DM. Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models. Oncogene. January 2008;27(1):85-97. Full Text – Open Access Publication Date January 2008 How Analyze was Used…