Tag Archives: Microcirculation

Molecular Targeting of Renal Inflammation using Drug Delivery Technology to Inhibit NF-kB Improves Renal Recovery in Chronic Kidney Disease

Alejandro R. Chade et al. Molecular Targeting of Renal Inflammation using Drug Delivery Technology to Inhibit NF-kB Improves Renal Recovery in Chronic Kidney Disease. American Journal of Physiology-Renal Physiology. Publication Date June 15, 2020 How Analyze was Used “Manually traced regions of interest from each kidney and each region were selected and time-density curves were…

Biopolymer-Delivered Vascular Endothelial Growth Factor Improves Renal Outcomes Following Revascularization

Erika Guise et al. Biopolymer-Delivered Vascular Endothelial Growth Factor Improves Renal Outcomes Following Revascularization. American Journal of Physiology-Renal Physiology. Publication Date March 20, 2019 How Analyze was Used “Kidney samples were scanned at 0.3°increments using a micro-CT scanner and reconstructed at 9μm resolution for image analysis. Using the Analyze software, the spatial density of microvessels…

The Metabolic syndrome does not affect development of collateral circulation in the post-stenotic swine kidney

Xin Zhang et al. The Metabolic syndrome does not affect development of collateral circulation in the post-stenotic swine kidney. American Journal of Hypertension. Publication Date August 9 2018 How Analyze was Used “MDCT images were reconstructed and displayed with the Analyze software package. For data analysis, regions of interest (ROI) were selected from tomographic images.”…

Obesity-metabolic derangement exacerbates cardiomyocyte loss distal to moderate coronary artery stenosis in pigs without affecting global cardiac function

Li ZL, Ebrahimi B, Zhang X, Eirin A, Woollard JR, Tang H, Lerman A, Wang SM, Lerman LO. Obesity-metabolic derangement exacerbates cardiomyocyte loss distal to moderate coronary artery stenosis in pigs without affecting global cardiac function. Am J Physiol Heart Circ Physiol. April 2014;306(7):H1087-1101. Publication Date April 2014 How Analyze was Used “Images were analyzed…

Disparate effects of single endothelin-A and -B receptor blocker therapy on the progression of renal injury in advanced renovascular disease

Chade AR, Stewart NJ, Peavy PR. Disparate effects of single endothelin-A and -B receptor blocker therapy on the progression of renal injury in advanced renovascular disease. Kidney Int. April 2014;85(4):833-844. Publication Date April 2014 How Analyze was Used “Images were analyzed with…Analyze®… The cortex and medulla were tomographically divided and the spatial density and distribution…

Selective improvement in renal function preserved remote myocardial microvascular integrity and architecture in experimental renovascular disease

Urbieta-Caceres VH, Zhu XY, Jordan KL, Tang H, Textor K, Lerman A, Lerman LO. Selective improvement in renal function preserved remote myocardial microvascular integrity and architecture in experimental renovascular disease. Atherosclerosis. April 2012;221(2):350-358. Full Text – Open Access Publication Date April 2012 How Analyze was Used “The images were analyzed with the Analyze® software package.”…

Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect

Mannheim D, Herrmann J, Bonetti PO, Lavi R, Lerman LO, Lerman A. Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect. Atherosclerosis. June 2011;216(2):283-291. Full Text – Open Access Publication Date June 2011 How Analyze was Used “The images were reconstructed and analyzed using Analyze® software package… [Bonetti et al. 2002,…

Revascularization of swine renal artery stenosis improves renal function but not the changes in vascular structure

Favreau F, Zhu XY, Krier JD, Lin J, Warner L, Textor SC, Lerman LO. Revascularization of swine renal artery stenosis improves renal function but not the changes in vascular structure. Kidney Int. December 2010;78(11):1110-1118. Full Text – Open Access Publication Date December 2010 How Analyze was Used “MDCT images were reconstructed and displayed with the…

Progressive renal vascular proliferation and injury in obese Zucker rats

Iliescu R, Chade AR. Progressive renal vascular proliferation and injury in obese Zucker rats. Microcirculation. May 2010;17(4):250-258. Publication Date May 2010 How Analyze was Used “The kidney samples were scanned at 0.3° increments using a micro-CT scanner, (SkyScan 1076 system, Micro Photonics Inc, PA) and the X-ray transmission images were acquired in each angle of…

Myocardial microvascular function during acute coronary artery stenosis: effect of hypertension and hypercholesterolaemia

Zhu XY, Daghini E, Chade AR, Versari D, Krier JD, Textor KB, Lerman A, Lerman LO. Myocardial microvascular function during acute coronary artery stenosis: effect of hypertension and hypercholesterolaemia. Cardiovasc Res. July 2009;83(2):371-380. Full Text – Open Access Publication Date July 2009 How Analyze was Used “All EBCT images were reconstructed using a filtered back-projection…