Tag Archives: Half-Life

Half-Life Extension Enhances Drug Efficacy in Adeno-Associated Virus Delivered Gene Therapy

Huifang Wu et al. Half-Life Extension Enhances Drug Efficacy in Adeno-Associated Virus Delivered Gene Therapy Engineering. Publication Date March 22, 2022 How Analyze was Used “Image segmentation was conducted using a volume-editing tool and volumes were quantified using the region of interest module within the software package (AnalyzeDirect, USA). Adipose content and distribution were calculated…

A combined accelerator mass spectrometry-positron emission tomography human microdose study with 14C- and 11C-labelled verapamil

Wagner CC, Simpson M, Zeitlinger M, Bauer M, Karch R, Abrahim A, Feurstein T, Schütz M, Kletter K, Müller M, Lappin G, Langer O. A combined accelerator mass spectrometry-positron emission tomography human microdose study with 14C- and 11C-labelled verapamil. Clin Pharmacokinet. February 2011;50(2):111-120. Full Text – Open Access Publication Date February 2011 How Analyze was…

Positron emission tomography of [18F]-big endothelin-1 reveals renal excretion but tissue-specific conversion to [18F]-endothelin-1 in lung and liver

Johnström P, Fryer TD, Richards HK, Maguire JJ, Clark JC, Pickard JD, Davenport AP. Positron emission tomography of [18F]-big endothelin-1 reveals renal excretion but tissue-specific conversion to [18F]-endothelin-1 in lung and liver. Br J Pharmacol. February 2010;159(4):812-819. Full Text – Open Access Publication Date February 2010 How Analyze was Used “Regions of interest were delineated…

In vivo monitoring of inflammatory cell mobilization to heart following myocardial infarction

Hu TCC, Bao W, Lenhard SC, Schaeffer TR, Mirabile RC, Jacobs P, Yue TL, Willette RN, Jucker BM. In vivo monitoring of inflammatory cell mobilization to heart following myocardial infarction. Paper presented at: International Society for Magnetic Resonance in Medicine; May 2004; Kyoto, Japan. Publication Date May 2004 How Analyze was Used “Image analysis was…