Tag Archives: Dopamine/metabolism

The catechol-O-methyltransferase Val158Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson’s disease: a PET study

Wu K, O’Keeffe D, Politis M, O’Keeffe GC, Robbins TW, Bose SK, Brooks DJ, Piccini P, Barker RA. The catechol-O-methyltransferase Val158Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson’s disease: a PET study. Brain. August 2012;135(Pt 8):2449-2457. Full Text – Open Access Publication Date August 2012 How Analyze was Used “Each object map was applied…

Limbic striatal dopamine D2/3 receptor availability is associated with non-planning impulsivity in healthy adults after exclusion of potential dissimulators

Reeves SJ, Polling C, Stokes PRA, Lappin JM, Shotbolt PP, Mehta MA, Howes OD, Egerton A. Limbic striatal dopamine D2/3 receptor availability is associated with non-planning impulsivity in healthy adults after exclusion of potential dissimulators. Psychiatry Res. April 2012;202(1):60-64. Publication Date April 2012 How Analyze was Used “The transformed VOI map was used to sample…

Significant decreases in frontal and temporal [11C]-raclopride binding after THC challenge

Stokes PRA, Egerton A, Watson B, Reid A, Breen G, Lingford-Hughes A, Nutt DJ, Mehta MA. Significant decreases in frontal and temporal [11C]-raclopride binding after THC challenge. Neuroimage. October 2010;52(4):1521-1527. Publication Date October 2010 How Analyze was Used “The ROIs were spatially normalised from standard space to individual space by applying the deformation matrix previously…

Acute effect of the anti-addiction drug bupropion on extracellular dopamine concentrations in the human striatum: an [11C]raclopride PET study

Egerton A, Shotbolt JP, Stokes PRA, Hirani E, Ahmad R, Lappin JM, Reeves SJ, Mehta MA, Howes OD, Grasby PM. Acute effect of the anti-addiction drug bupropion on extracellular dopamine concentrations in the human striatum: an [11C]raclopride PET study. Neuroimage. March 2010;50(1):260-266. Full Text – Open Access Publication Date March 2010 How Analyze was Used…

Can recreational doses of THC produce significant dopamine release in the human striatum?

Stokes PRA, Mehta MA, Curran HV, Breen G, Grasby PM. Can recreational doses of THC produce significant dopamine release in the human striatum? Neuroimage. October 2009;48(1):186-190. Publication Date October 2009 How Analyze was Used “The deformed striatal atlas was used to sample counts from the add image using Analyze 8.0 software (www.analyzedirect.com).” Keywords Adult Analysis…

Changes in gray matter density in fibromyalgia: correlation with dopamine metabolism

Wood PB, Glabus MF, Simpson R, Patterson JC, 2nd. Changes in gray matter density in fibromyalgia: correlation with dopamine metabolism. J Pain. June 2009;10(6):609-618. Publication Date June 2009 How Analyze was Used “PET data was reconstructed using FORE iterative reconstruction and segmented attenuation correction. Image data from the last 20 minutes of acquisition was summed,…

Striatal dopaminergic denervation and gait in healthy adults

Cham R, Studenski SA, Perera S, Bohnen NI. Striatal dopaminergic denervation and gait in healthy adults. Exp Brain Res. March 2008;185(3):391-398. Publication Date March 2008 How Analyze was Used “The MR data was cropped in preparation for alignment with the PET data using AnalyzeAVW software.” Keywords Adult Aged Aged, 80 and over Aging/metabolism Corpus Striatum/physiology…

Striatal dopamine denervation and sensory integration for balance in middle-aged and older adults

Cham R, Perera S, Studenski SA, Bohnen NI. Striatal dopamine denervation and sensory integration for balance in middle-aged and older adults. Gait Posture. October 2007;26(4):516-525. Publication Date October 2007 How Analyze was Used “The MR data was cropped in preparation for alignment with the PET data using AnalyzeAVW software.” Keywords Accidental Falls Adult Aged Aged,…

Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson’s disease

Boska MD, Hasan KM, Kibuule D, Banerjee R, McIntyre E, Nelson JA, Hahn T, Gendelman HE, Mosley RL. Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson’s disease. Neurobiol Dis. June 2007;26(3):590-596. Full Text – Open Access Publication Date June 2007 How Analyze was Used “3D MRI scans were zero-filled…

Measurement of methylphenidate-induced change in extrastriatal dopamine concentration using [11C]FLB 457 PET

Montgomery AJ, Asselin MC, Farde L, Grasby PM. Measurement of methylphenidate-induced change in extrastriatal dopamine concentration using [11C]FLB 457 PET. J Cereb Blood Flow Metab. February 2007;27(2):369-377. Full Text – Open Access Publication Date February 2007 How Analyze was Used “Tissue TAC’s [ time–activity curves] were generated by overlaying these ROI on the dynamic PET…