AnalyzeDirect Montgomery AJ, Asselin MC, Farde L, Grasby PM. Measurement of methylphenidate-induced change in extrastriatal dopamine concentration using [11C]FLB 457 PET. J Cereb Blood Flow Metab. February 2007;27(2):369-377.
Full Text – Open Access
Publication Date
February 2007
How Analyze was Used
“Tissue TAC’s [ time–activity curves] were generated by overlaying these ROI on the dynamic PET images using the image analysis software Analyze AVW 3.0.”
Keywords
Adult
Affect/drug effects
Algorithms
Carbon Radioisotopes/blood/diagnostic use
Cerebral Cortex/drug effects/metabolism/radionuclide imaging
Dopamine/metabolism
Dopamine Antagonists/blood/diagnostic use
Dopamine Uptake Inhibitors/pharmacology
Double-Blind Method
Humans
Kinetics
Male
Methylphenidate/pharmacology
Positron-Emission Tomography (PET)
Pyrrolidines/blood/diagnostic use
Radiopharmaceuticals/blood/diagnostic use
Salicylamides/blood/diagnostic use
Author Affiliation(s)
MRC Clinical Sciences Centre, Cyclotron Building, Imperial College, Hammersmith Hospital, London, UK. (AJM, PMG)
Hammersmith Imanet, Cyclotron Building, Hammersmith Hospital, London, UK. (M-CA)
Psychiatry Section, Department of Clinical Neurosciences, Karolinska Hospital, Stockholm, Sweden. (LF)
ID# 1770
Tags: Adult, Affect/drug effects, Algorithms, Carbon Radioisotopes/blood/diagnostic use, Cerebral Cortex/drug effects/metabolism/radionuclide imaging, Dopamine Antagonists/blood/diagnostic use, Dopamine Uptake Inhibitors/pharmacology, Dopamine/metabolism, Double-Blind Method, Humans, Kinetics, Male, Methylphenidate/pharmacology, Positron Emission Tomography (PET), Pyrrolidines/blood/diagnostic use, Radiopharmaceuticals/blood/diagnostic use, Salicylamides/blood/diagnostic use