AnalyzeDirect Holst CR, Bou-Reslan H, Gore BB, Wong K, Grant D, Chalasani S, Carano RA, Frantz GD, Tessier-Lavigne M, Bolon B, French DM, Ashkenazi A. Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival. PLoS One. June 2007;2(6):e575.
Full Text – Open Access
Publication Date
June 2007
How Analyze was Used
“Three-dimensional (3D) surface renderings were created from the µCT data with the use of Analyze (AnalyzeDirect Inc., Lenexa, KS), an image analysis software package.”
Keywords
Animals
Animals, Newborn/growth & development
Cells, Cultured
Embryo, Mammalian/cytology/metabolism
Embryonic Development
Female
Fibroblasts/cytology/metabolism
Genes, Lethal/physiology
Heparan Sulfate Proteoglycans/metabolism
In Situ Hybridization
Kidney/abnormalities
Mice
Mice, Inbred C57BL
Mice, Knockout
Muscle, Skeletal/abnormalities
Pregnancy
Signal Transduction
Sulfatases/physiology
Sulfotransferases/physiology
Survival Rate
Author Affiliation(s)
Department of Molecular Oncology, Genentech, Inc., South San Francisco, CA, US. (CRH, AA)
Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA, US. (HBR, RAC)
Department of Research Drug Discovery, Genentech, Inc., South San Francisco, CA, US. (BBG, KW, MTL)
Department of Molecular Biology, Genentech, Inc., South San Francisco, CA, US. (DG)
Department of Pathology, Genentech, Inc., South San Francisco, CA, US. (SC, GDF, DMF)
Graduate Program in Neurosciences, Stanford University, Stanford, CA, US. (BBG)
GEMpath, Inc., Cedar City, UT, US. (BB)
ID# 1777
Tags: Animals, Cultured Cells, Embryonic Development, Female, Fibroblasts/cytology/metabolism, Heparan Sulfate Proteoglycans/metabolism, In Situ Hybridization, Inbred C57BL Mice, Kidney/abnormalities, Knockout Mice, Lethal Genes/physiology, Mammalian Embryo/cytology/metabolism, Mice, Newborn Animals/growth & development, Pregnancy, Signal Transduction, Skeletal Muscle/abnormalities, Sulfatases/physiology, Sulfotransferases/physiology, Survival Rate