Tag Archives: Signal Transduction

A FAK scaffold inhibitor disrupts FAK and VEGFR-3 signaling and blocks melanoma growth by targeting both tumor and endothelial cells

Kurenova E, Ucar D, Liao J, Yemma M, Gogate P, Bshara W, Sunar U, Seshadri M, Hochwald SN, Cance WG. A FAK scaffold inhibitor disrupts FAK and VEGFR-3 signaling and blocks melanoma growth by targeting both tumor and endothelial cells. Cell Cycle. October 2014;13(16):2542-2553. Publication Date October 2014 How Analyze was Used “Raw image datasets…

Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway

Leow CC, Wang BE, Ross J, Chan SM, Zha J, Carano RAD, Frantz G, Shen MM, de Sauvage FJ, Gao WQ. Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway. J Biol Chem. July 2009;284(31):21057-21065. Full Text – Open Access Publication Date July 2009 How Analyze was Used “Micro-CT…

Differences in muscle protein synthesis and anabolic signaling in the postabsorptive state and in response to food in 65-80 year old men and women

Smith GI, Atherton P, Villareal DT, Frimel TN, Rankin D, Rennie MJ, Mittendorfer B. Differences in muscle protein synthesis and anabolic signaling in the postabsorptive state and in response to food in 65-80 year old men and women. PLoS One. March 2008;3(3):e1875. Full Text – Open Access Publication Date March 2008 How Analyze was Used…

Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival

Holst CR, Bou-Reslan H, Gore BB, Wong K, Grant D, Chalasani S, Carano RA, Frantz GD, Tessier-Lavigne M, Bolon B, French DM, Ashkenazi A. Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival. PLoS One. June 2007;2(6):e575. Full Text – Open Access Publication Date June 2007 How Analyze was Used…

Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus

Merchant M, Evangelista M, Luoh SM, Frantz GD, Chalasani S, Carano RAD, van Hoy M, Ramirez J, Ogasawara AK, McFarland LM, Filvaroff EH, French DM, de Sauvage FJ. Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus. Mol Cell Biol. August 2005;25(16):7054-7068. Full Text – Open Access…

Rapid internalization and recycling of the human neuropeptide Y Y1 receptor

Gicquiaux H, Lecat S, Gaire M, Dieterlen A, Mély Y, Takeda K, Bucher B, Galzi JL. Rapid internalization and recycling of the human neuropeptide Y Y1 receptor. J Biol Chem. February 2002;277(8):6645-6655. Full Text – Open Access Publication Date February 2002 How Analyze was Used “Co-localization analysis was done using AnalyzeAVW 3.0 software installed on…