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Pavese N, Gerhard A, Tai YF, Ho AK, Turkheimer F, Barker RA, Brooks DJ, Piccini P. Microglial activation correlates with severity in Huntington disease: a clinical and PET study. Neurology. June 2006;66(11):1638-1643.

Publication Date
June 2006

How Analyze was Used
“The standard object map contained regions defined for hypothalamus, frontal, parietal, temporal, and occipital lobes that had been traced free hand onto the Montreal Neurologic Institute (MNI) single-subject MRI in standard space found in the SPM’99 package using ANALYZE software (Analyze AVW).”

Keywords
Adult
Aged
Amides/diagnostic use/pharmacokinetics
Corpus Striatum/metabolism/radionuclide imaging
Female
Humans
Huntington Disease/metabolism/radionuclide imaging
Isoquinolines/diagnostic use/pharmacokinetics
Male
Microglia/metabolism/radionuclide imaging
Middle Aged
Positron-Emission Tomography (PET)/methods
Raclopride/diagnostic use/pharmacokinetics
Radiopharmaceuticals/diagnostic use/pharmacokinetics
Reproducibility of Results
Sensitivity and Specificity
Severity of Illness Index
Statistics as Topic

Author Affiliation(s)
MRC Clinical Sciences Centre and Division of Neuroscience, University of Cambridge, UK. (NP, AG, YFT, FT, DJB, PP)

Faculty of Medicine, Imperial College, Hammersmith Hospital, London, and Centre for Brain Repair and Department of Neurology, University of Cambridge, UK. (AKH, RAB)

ID# 2003

Tags: Adult, Aged, Amides/diagnostic use/pharmacokinetics, Corpus Striatum/metabolism/radionuclide imaging, Female, Humans, Huntington Disease/metabolism/radionuclide imaging, Isoquinolines/diagnostic use/pharmacokinetics, Male, Microglia/metabolism/radionuclide imaging, Middle Aged, Positron-Emission Tomography (PET)/methods, Raclopride/diagnostic use/pharmacokinetics, Radiopharmaceuticals/diagnostic use/pharmacokinetics, Reproducibility of Results, Sensitivity and Specificity, Severity of Illness Index, Statistics as Topic