AnalyzeDirect Bidar AW, Ploj K, Lelliott C, Nelander K, Winzell MS, Böttcher G, Oscarsson J, Storlien L, Hockings PD. In vivo imaging of lipid storage and regression in diet-induced obesity during nutrition manipulation. Am J Physiol Endocrinol Metab. December 2012;303(11):E1287-1295.
Full Text – Open Access
Publication Date
December 2012
How Analyze was Used
“Adipose tissue compartments were segmented semiautomatically using the image analysis software Analyze 6.0.”
Keywords
Adipose Tissue/metabolism/radiography
Animal Feed
Animals
Body Composition
Body Fat Distribution/instrumentation
Cross-Sectional Studies
Disease Models, Animal
Energy Metabolism/physiology
Female
Imaging, Three-Dimensional/veterinary
Insulin Resistance/physiology
Liver/metabolism/radiography
Longitudinal Studies
Magnetic Resonance Imaging (MRI)/veterinary
Magnetic Resonance Spectroscopy
Mice
Mice, Inbred C57BL
Obesity/blood/metabolism/radiography
Phenotype
Random Allocation
Triglycerides/blood
Author Affiliation(s)
PHB Imaging, AstraZeneca R&D, Mölndal, Sweden. (AWB, PDH)
CVGI Bioscience, AstraZeneca R&D, Mölndal, Sweden. (KP, CL, MSW, JO)
Discovery Sciences, Statistics, AstraZeneca R&D Mölndal, Sweden. (KN)
Safety Assessment, AstraZeneca R&D, Mölndal, Sweden. (GB)
Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, University of Sydney, Sydney, Australia. (LS)
ID# 619
Tags: Adipose Tissue/metabolism/radiography, Animal Disease Models, Animal Feed, Animals, Body Composition, Body Fat Distribution/instrumentation, Cross Sectional Studies, Energy Metabolism/physiology, Female, Inbred C57BL Mice, Insulin Resistance/physiology, Liver/metabolism/radiography, Longitudinal Studies, Magnetic Resonance Imaging (MRI)/veterinary, Magnetic Resonance Spectroscopy, Mice, Obesity/blood/metabolism/radiography, Phenotype, Random Allocation, Three-Dimensional Imaging/veterinary, Triglycerides/blood