AnalyzeDirect Jell J, Merali S, Hensen ML, Mazurchuk R, Spernyak JA, Diegelman P, Kisiel ND, Barrero C, Deeb KK, Alhonen L, Patel MS, Porter CW. Genetically altered expression of spermidine/spermine N1-acetyltransferase affects fat metabolism in mice via acetyl-CoA. J Biol Chem. March 2007;282(11):8404-8413.
Full Text – Open Access
Publication Date
March 2007
How Analyze was Used
“Image segmentation of fat from whole body data sets was performed through the creation of object maps using Analyze 5.0 (AnalyzeDirect, Lenexa, KS).”
Keywords
Acetyl Coenzyme A/metabolism
Acetyltransferases/genetics/physiology
Adipose Tissue/metabolism
Animals
Fatty Acids/metabolism
Female
Glucose/metabolism
Leptin/blood
Liver/metabolism
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Models, Biological
Oxygen/metabolism
Phenotype
Polyamines/metabolism
Author Affiliation(s)
Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, NY14263, US. (JJ, MLH, PD, NDK, KKD, CWP)
Department of Cancer Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (RM, JAS)
Fels Institute and Biochemistry Department, Temple University School of Medicine, Philadelphia, PA 19140, US. (SM, CB)
A. I. Virtanen Institute for Molecular Sciences, University of Kuopio, FI-70211 Kuopio, Finland. (LA)
Department of Biochemistry, State University of New York at Buffalo School of Medicine, Buffalo, NY 14214, US. (MSP)
ID# 1664
Tags: Acetyl Coenzyme A/metabolism, Acetyltransferases/genetics/physiology, Adipose Tissue/metabolism, Animals, Biological Models, Fatty Acids/metabolism, Female, Glucose/metabolism, Inbred C57BL Mice, Knockout Mice, Leptin/blood, Liver/metabolism, Male, Mice, Oxygen/metabolism, Phenotype, Polyamines/metabolism