AnalyzeDirect Wadghiri YZ, Li J, Wang J, Hoang DM, Sun Y, Xu H, Tsui W, Li Y, Boutajangout A, Wang A, de Leon M, Wisniewski T. Detection of amyloid plaques targeted by bifunctional USPIO in Alzheimer’s disease transgenic mice using magnetic resonance microimaging. PLoS One. February 2013;8(2):e57097.
Full Text – Open Access
Publication Date
February 2013
How Analyze was Used
“The advantage of the 3D-imaging approach is that the image set can be reprocessed in any desired slice orientation using Analyze software (AnalyzeDirect, Overland Park, KS), facilitating image comparison during co-registration with histology.”
Keywords
Alzheimer Disease/diagnosis/pathology
Amyloid beta-Peptides/chemistry
Animals
Brain/pathology
Contrast Media
Disease Models, Animal
Magnetic Resonance Imaging (MRI)
Magnetite Nanoparticles/administration & dosage/adverse effects/chemistry/diagnostic use
Mice
Mice, Transgenic
Plaque, Amyloid/pathology
Author Affiliation(s)
Department of Radiology, New York University School of Medicine, New York, NY US. (YZW, DMH)
Department of Neurology, New York University School of Medicine, New York, NY, US. (YS, YL, AB, TW)
Department of Psychiatry, New York University School of Medicine, New York, NY, US. (WT, ML, TW)
Department of Pathology, New York University School of Medicine, New York, NY, US. (TW)
Nathan Kline Institute, Orangeburg, NY, US. (ML)
Ocean NanoTech, LLC, Springdale, AR, US. (HX, AW)
Tianjin Huanhu Hospital, Tianjin, China. (JL, JW)
ID# 397
Tags: Alzheimer Disease/diagnosis/pathology, Amyloid beta-Peptides/chemistry, Amyloid Plaque/pathology, Animal Disease Models, Animals, Brain/pathology, Contrast Media, Magnetic Resonance Imaging (MRI), Magnetite Nanoparticles/administration & dosage/adverse effects/chemistry/diagnostic use, Mice, Transgenic Mice