Langheinrich AC, Michniewicz A, Sedding DG, Walker G, Beighley PE, Rau WS, Bohle RM, Ritman EL. Correlation of vasa vasorum neovascularization and plaque progression in aortas of apolipoprotein E(-/-)/low-density lipoprotein(-/-) double knockout mice. Arterioscler Thromb Vasc Biol. February 2006;26(2):347-352.
Full Text – Open Access
Publication Date
February 2006
How Analyze was Used
“The aorta and lung were scanned en bloc by micro-CT systems described recently [Jorgensen et al 1998, Langheinrich et al. 2004]. The resulting 3-dimensional images were displayed using image analysis software (Analyze 6.0).”
Keywords
Animals
Aorta/pathology
Apolipoproteins E/genetics
Atherosclerosis/genetics/pathology
Disease Models, Animal
Disease Progression
Lipoproteins, LDL/genetics
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Neovascularization, Pathologic/genetics/pathology
Vasa Vasorum/pathology
Vasculitis/genetics/pathology
Author Affiliation(s)
Mayo Clinic College of Medicine, Rochester, MN, US. (ACL, PEB, ELR)
Justus-Liebig University, Giessen, Germany, US. (ACL, AM, DGS, GW, WSR, RMB)
ID# 1864
Tags: Animal Disease Models, Animals, Aorta/pathology, Apolipoproteins E/genetics, Atherosclerosis/genetics/pathology, Disease Progression, Inbred C57BL Mice, Knockout Mice, LDL Lipoproteins/genetics, Male, Mice, Pathologic Neovascularization/genetics/pathology, Vasa Vasorum/pathology, Vasculitis/genetics/pathology