AnalyzeDirect Pirko I, Cardin R, Chen Y, Lohrey AK, Lindquist DM, Dunn RS, Zivadinov R, Johnson AJ. CMV infection attenuates the disease course in a murine model of multiple sclerosis. PLoS One. February 2012;7(2):e32767.
Full Text – Open Access
Publication Date
February 2012
How Analyze was Used
“Volumetric analysis using the 3D ROI tool was conducted using the Analyze software package…[Robb 1999, Robb 2001].”
Keywords
Animals
Antigens, CD3/biosynthesis
Antigens, CD45/biosynthesis
Antigens, CD8/biosynthesis
Brain/pathology
Cytomegalovirus Infections/complications/therapy/virology
Demyelinating Diseases/virology
Disease Models, Animal
Encephalitis/virology
Female
Flow Cytometry/methods
Immune System
Inflammation
Mice
Multiple Sclerosis/complications/therapy/virology
Reproducibility of Results
Time Factors
Author Affiliation(s)
Department of Neurology, Mayo Clinic, Rochester, MN, US. (IP)
Division of Infectious Diseases, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, US. (RC)
Department of Neurology and Immunology, Mayo Clinic, Rochester, MN, US. (YC, AKL, AJJ)
Imaging Research Center, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, US. (AML, RSD)
Department of Neurology and Buffalo Neuroimaging Analysis Center, University of Buffalo, Buffalo, NY, US. (RZ)
ID# 592
Tags: Animal Disease Models, Animals, Brain/pathology, CD3 Antigens/biosynthesis, CD45 Antigens/biosynthesis, CD8 Antigens/biosynthesis, Cytomegalovirus Infections/complications/therapy/virology, Demyelinating Diseases/virology, Encephalitis/virology, Female, Flow Cytometry/methods, Immune System, Inflammation, Mice, Multiple Sclerosis/complications/therapy/virology, Reproducibility of Results, Time Factors