AnalyzeDirect Drouin-Ouellet J, Sawiak SJ, Cisbani G, Lagacé M, Kuan WL, Saint-Pierre M, Dury RJ, Alata W, St-Amour I, Mason SL, Calon F, Lacroix S, Gowland PA, Francis ST, Barker RA, Cicchetti F. Cerebrovascular and blood-brain barrier impairments in Huntington’s disease: potential implications for its pathophysiology. Ann Neurol. April 2015.
Publication Date
April 2015
How Analyze was Used
“Hand-drawn regions of interest (ROIs) for the caudate and putamen were used to extract mean values. ROIs were produced using Analyze 12.”
Keywords
Blood Vessels/injuries
Blood Brain Barrier/injuries
Disease Models, Animal
Humans
Huntington Disease/physiopathology
Magnetic Resonance Imaging (MRI)
Mice
Author Affiliation(s)
Department of Clinical Neurosciences, John van Geest Centre for Brain Repair, University of Cambridge, Cambridge, UK. (JDO, WLK, SLM, RAB)
Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK. (SJS)
Centre de recherche du CHU de Québec (CHUQ), Québec, Québec, Canada. (GC, ML, MSP, WA, ISA, FCalon, SL, FCicchetti)
Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK. (RJD, PAG, STF)
Faculté de Pharmacie, Université Laval, Québec, Québec, Canada. (FCalon)
Département de Médecine Moléculaire, Université Laval, Québec, Québec, Canada. (SL)
Département de Psychiatrie & Neurosciences, Université Laval, Québec, Québec, Canada. (FCicchetti)
ID# 2231
Tags: Animal Disease Models, Blood Brain Barrier/injuries, Blood Vessels/injuries, Humans, Huntington Disease/physiopathology, Magnetic Resonance Imaging (MRI), Mice