AnalyzeDirect Carlsson F, Kim J, Dumitru C, Barck KH, Carano RAD, Sun M, Diehl L, Brown EJ. Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection. PLoS Pathog. May 2010;6(5):e1000895.
Full Text – Open Access
Publication Date
May 2010
How Analyze was Used
“Mean bone volume within the segmented bone was measured for each vertebra, and the average bone volume was calculated for each animal. Image analysis was performed using [the] Analyze software package (AnalyzeDirect, Inc., Lenexa, KS, USA).”
Keywords
Animals
Bacterial Proteins/genetics/immunology/metabolism
Carrier Proteins/genetics/metabolism
Cells, Cultured
Cytoskeletal Proteins/genetics/metabolism
Disease Models, Animal
Female
Host-Pathogen Interactions/immunology
Inflammation/immunology/microbiology
Interleukin-1beta/secretion
Macrophages/cytology/immunology/microbiology
Mice
Mice, Inbred C57BL
Mice, Knockout
Mycobacterium Infections, Nontuberculous/immunology/microbiology
Mycobacterium marinum/growth & development/immunology/pathogenicity
Phagosomes/immunology
Tail/microbiology
Tuberculoma/immunology/microbiology
Virulence
Virulence Factors/genetics/immunology/metabolism
Author Affiliation(s)
Department of Microbial Pathogenesis, Genentech Inc., South San Francisco, CA, US. (FC, EJB)
Department of Translational Immunology, Genentech Inc., South San Francisco, CA, US. (JK, CD)
Department of Biomedical Imaging, Genentech Inc., South San Francisco, CA, US. (KHB, RADC)
Department of Pathology, Genentech Inc., South San Francisco, CA, US. (MS, LD)
ID# 1150
Tags: Animal Disease Models, Animals, Bacterial Proteins/genetics/immunology/metabolism, Carrier Proteins/genetics/metabolism, Cultured Cells, Cytoskeletal Proteins/genetics/metabolism, Female, Host-Pathogen Interactions/immunology, Inbred C57BL Mice, Inflammation/immunology/microbiology, Interleukin-1beta/secretion, Knockout Mice, Macrophages/cytology/immunology/microbiology, Mice, Mycobacterium marinum/growth & development/immunology/pathogenicity, Nontuberculous Mycobacterium Infections/immunology/microbiology, Phagosomes/immunology, Tail/microbiology, Tuberculoma/immunology/microbiology, Virulence, Virulence Factors/genetics/immunology/metabolism