The Analyze Blog

Single Neuron Unit and Local Field Potential Activity in Visual Memory

Neurons

Neurons are electrically excitable cells that encode information and transmit it to neighboring neurons through synaptic connections. Current neurotechnologies are focusing on finding new ways to simultaneously record the activity of both single neurons and connected neural networks. A recent study from the Department of Neurology at Mayo Clinic explored and compared single neuron spiking…

Obesity and Hippocampal Atrophy

Obesity_and_Hippocampal_Atrophy

Recent data shows that worldwide obesity has more than doubled since 1980. In 2014, almost 2 billion adults were overweight and of these, over 600 million were obese (World Health Organization). Evidence indicates that obesity is not only a major risk factor for conditions such as cardiovascular diseases, diabetes, and musculoskeletal disorders, but also a…

The Thalamus as a Biomarker in Neurodegenerative Disorders

Thalamus

The human brain is made of an elaborate network of interlinked regions that communicate through strategic hubs. Several studies have shown that disturbances of the structural and functional connectivity profile provided by brain hubs are often linked to neuropathologies. The thalamus has been described in the literature as the gateway to subcortical neural connections, as…

Predicting Tibial Subchondral Bone Stiffness in Osteoarthritis

Osteoarthritis

Osteoarthritis is a progressive degenerative joint disorder seen especially among older people that mostly affects cartilage, the tissue that covers the ends of bones forming a joint. Healthy cartilage allows bones to glide over one another and absorbs energy from the shock of physical movement. In osteoarthritis, cartilage breaks and wears away, allowing the bones…

Magnetic Resonance Spectroscopy for the Assessment of Temporal Lobe Epilepsy

Temporal_Lobe_Epilepsy

Magnetic resonance imaging (MRI) offers valuable structural information about organs and tissues in the body, providing high-resolution images that help diagnose a wide range of conditions and dysfunctions. However, data underlying functional activity of the structure is often limited. Proton magnetic resonance spectroscopy (MRS) is a non-invasive, in vivo technique complementary to MRI that interrogates…

Water Vapor Treatment for Benign Prostatic Hyperplasia

Prostatic_Hyperplasia

Benign prostatic hyperplasia commonly occurs in older men and consists of an enlargement of the prostate, a walnut-shaped gland that surrounds the urethra at the neck of the bladder. This abnormal growth may compress or completely block the urethra, causing a wide range of lower urinary tract symptoms that can lead to bladder outlet obstruction and…

Corpus Callosum Development in Autism is Different for Girls

Autism

Autism is a global problem with skyrocketing incidence rates. The CDC reports that 1 in 68 children born today will be diagnosed with autism spectrum disorder (ASD). The incidence for boys is 1 in 42, so the majority of research studies has focused on males. This has led to a poorly understood and little-studied population of…

Visualizing Calcified Plaques with Virtual Intravascular Endoscopy

Virtual_Intravascular_Endoscopy

Searching for screening techniques for the early detection of coronary artery disease, the leading cause of death in the Western world, represents one of the greatest challenges in the scientific field. While the occurrence of cardiovascular disease can be detected through imaging modalities such as coronary CT angiography, the presence of calcified plaques in the…

The Role of Microvasculature in Myocardial Perfusion

Microvasculature

Myocardial perfusion is the process by which blood is supplied to the heart muscle from the left and right coronary arteries. Exploring the structure of microvascular trees in a detailed way will provide a deeper understanding of the mechanisms that rule myocardial perfusion. Researchers from Western University, London, investigated arteriolar trees, the pre-capillary levels of the microvasculature,…

Enhanced Contrast MRI for the Prevention of Renal Graft Rejection

Dialysis

Transplantation of an organ from a donor who differs genetically from the recipient induces an immune response that, if not controlled, may compromise the graft outcome. Chronic rejection is a major complication in renal transplantation and is currently the most prevalent cause of renal transplant failure. Current research is focused on developing new noninvasive imaging…