AnalyzeDirect

Analyze Publications Database

Use of a vaccine strain of measles virus genetically engineered to produce carcinoembryonic antigen as a novel therapeutic agent against glioblastoma multiforme

Phuong LK, Allen C, Peng KW, Giannini C, Greiner S, TenEyck CJ, Mishra PK, Macura SI, Russell SJ, Galanis EC. Use of a vaccine strain of measles virus genetically engineered to produce carcinoembryonic antigen as a novel therapeutic agent against glioblastoma multiforme. Cancer Res. May 2003;63(10):2462-2469.

Full Text – Open Access

Publication Date
May 2003

How Analyze was Used
“Volumetric measurements of the intracranial tumors were obtained with MRI, using the region of interest method in Analyze 3.1.”

Keywords
Animals
Antigens, CD/biosynthesis/genetics/immunology
Antigens, CD46
Apoptosis/physiology
Brain Neoplasms/genetics/immunology/therapy
Cancer Vaccines/adverse effects/genetics/immunology/pharmacology
Carcinoembryonic Antigen/biosynthesis/blood/genetics/immunology
Cercopithecus aethiops
Genetic Engineering/methods
Glioblastoma/genetics/immunology/therapy
Humans
Measles Vaccine/adverse effects/genetics/immunology/pharmacology
Measles virus/genetics/ immunology
Membrane Glycoproteins/biosynthesis/genetics/immunology
Mice
Mice, Inbred BALB C
Mice, Nude
Mice, Transgenic
Tumor Cells, Cultured
Vero Cells
Xenograft Model Antitumor Assays

Author Affiliation(s)
Department of Neurosurgery, Mayo Clinic, Rochester, MN 55905, US. (LKP)

Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, US. (CA, KWP, SG, CJT, SR, EG)

Department of Pathology, Mayo Clinic, Rochester, MN 55905, US. (CG)

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, US. (PM, SIM)

Department of Oncology, Mayo Clinic, Rochester, MN 55905, US. (EG)

ID# 2444

Tags: , , , , , , , , , , , , , , , , , , , ,