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Barthel H, Perumal M, Latigo J, He Q, Brady F, Luthra SK, Price PM, Aboagye EO. The uptake of 3′-deoxy-3′-[¹⁸F]fluorothymidine into L5178Y tumours in vivo is dependent on thymidine kinase 1 protein levels. Eur J Nucl Med Mol Imaging. March 2005;32(3):257-263.

Publication Date
March 2005

How Analyze was Used
“The image data sets obtained were transferred to a SUN workstation … and visualised using the ANALYZE software (version 4.0).”

Keywords
Animals
Dideoxynucleosides/diagnostic use/pharmacokinetics
Lymphoma/metabolism/radionuclide imaging
Male
Metabolic Clearance Rate
Mice
Organ Specificity
Radiopharmaceuticals/diagnostic use/pharmacokinetics
Thymidine Kinase/metabolism
Tissue Distribution
Tumor Markers, Biological/metabolism

Author Affiliation(s)
Molecular Therapy and PET Oncology Research Group, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK. (HB, MP, JL, EOA)

Department of Nuclear Medicine, University of Leipzig, Liebigstrasse 20A, 04103, Leipzig, Germany. (HB)

Clinical Research Laboratory, Department of Oncology, Huddinge University Hospital, Karolinska Institute, 171 76, Stockholm, Sweden. (QH)

Hammersmith Imanet, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK. (FB, SKL)

Wolfson Molecular Imaging Centre, Christie Hospital NHS Trust, Wilmslow Road, Manchester, M20 4BX, UK. (PMP)

ID# 2109

Tags: Animals, Biological Tumor Markers/metabolism, Dideoxynucleosides/diagnostic use/pharmacokinetics, Lymphoma/ metabolism/radionuclide imaging, Male, Metabolic Clearance Rate, Mice, Organ Specificity, Radiopharmaceuticals/diagnostic use/pharmacokinetics, Thymidine Kinase/metabolism, Tissue Distribution