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Lekx KS, Prato FS, Sykes J, Wisenberg G. The partition coefficient of Gd-DTPA reflects maintained tissue viability in a canine model of chronic significant coronary stenosis. J Cardiovasc Magn Reson. January 2004;6(1):33-42.

Publication Date
January 2004

How Analyze was Used
“The change in signal intensity (DSI) from post- to precontrast in both the tissue regions and the blood pool was determined using AnalyzeAVW (Robb, 1990) and in vivo partition coefficient was thus determined as (Pereira et al., 1999).”

Keywords
Adrenergic beta-Agonists/administration & dosage/diagnostic use
Animals
Chronic Disease
Contrast Media/metabolism
Coronary Angiography
Coronary Circulation/physiology
Coronary Stenosis/diagnosis/physiopathology
Disease Models, Animal
Dobutamine/administration & dosage/diagnostic use
Dogs
Dose-Response Relationship, Drug
Echocardiography, Stress
Female
Follow-Up Studies
Gadolinium DTPA/diagnostic use/metabolism
Image Enhancement
Magnetic Resonance Angiography
Models, Cardiovascular
Myocardium/metabolism/pathology
Stroke Volume/physiology

Author Affiliation(s)
Department of Nuclear Medicine, Imaging Program, Lawson Health Research Institute, University of Western Ontario, London, Ontario, Canada. (KSL, FSP, JS)

Division of Cardiology and The Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada. (GW)

ID# 2330

Tags: Adrenergic beta-Agonists/administration & dosage/diagnostic use, Animal, Animals Disease Models, Cardiovascular Models, Chronic Disease, Contrast Media/metabolism, Coronary Angiography, Coronary Circulation/physiology, Coronary Stenosis/diagnosis/physiopathology, Dobutamine/administration & dosage/diagnostic use, Dogs, Drug Dose-Response Relationship, Female, Follow-Up Studies, Gadolinium DTPA/diagnostic use/metabolism, Image Enhancement, Magnetic Resonance Angiography, Myocardium/metabolism/pathology, Stress Echocardiography, Stroke Volume/physiology