Tag Archives: Drug Delivery Systems

Differential tumor-targeting abilities of three single-domain antibody formats

Bell A, Wang ZJ, Arbabi-Ghahroudi M, Chang TA, Durocher Y, Trojahn U, Baardsnes J, Jaramillo ML, Li S, Baral TN, O’Connor-McCourt M, Mackenzie R, Zhang J. Differential tumor-targeting abilities of three single-domain antibody formats. Cancer Lett. March 2010;289(1):81-90. Publication Date March 2010 How Analyze was Used “The calculated concentrations of radioactivity were multiplied by the…

Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor: insights from imaging

O’Connor JPB, Carano RAD, Clamp AR, Ross J, Ho CCK, Jackson A, Parker GJM, Rose CJ, Peale FV, Friesenhahn M, Mitchell CL, Watson Y, Roberts C, Hope L, Cheung S, Reslan HB, Go MAT, Pacheco GJ, Wu X, Cao TC, Ross S, Buonaccorsi GA, Davies K, Hasan J, Thornton P, del Puerto O, Ferrara N,…

Tumor vascular maturation and improved drug delivery induced by methylselenocysteine leads to therapeutic synergy with anticancer drugs

Bhattacharya A, Seshadri M, Oven SD, Tόth K, Vaughan MM, Rustum YM. Tumor vascular maturation and improved drug delivery induced by methylselenocysteine leads to therapeutic synergy with anticancer drugs. Clin Cancer Res. June 2008;14(12):3926-3932. Full Text – Open Access Publication Date June 2008 How Analyze was Used “For determination of vessel lumen area, photomicrographs of…

Quantitative magnetic resonance and SPECT imaging for macrophage tissue migration and nanoformulated drug delivery

Gorantla S, Dou H, Boska M, Destache CJ, Nelson J, Poluektova L, Rabinow BE, Gendelman HE, Mosley RL. Quantitative magnetic resonance and SPECT imaging for macrophage tissue migration and nanoformulated drug delivery. J Leukoc Biol. November 2006;80(5):1165-1174. Full Text – Open Access Publication Date November 2006 How Analyze was Used “Reconstructed SPECT images (green) were…

Lack of microvessels in well-differentiated regions of human head and neck squamous cell carcinoma A253 associated with functional magnetic resonance imaging detectable hypoxia, limited drug delivery, and resistance to irinotecan therapy

Bhattacharya A, Tóth K, Mazurchuk R, Spernyak JA, Slocum HK, Pendyala L, Azrak R, Cao S, Durrani FA, Rustum YM. Lack of microvessels in well-differentiated regions of human head and neck squamous cell carcinoma A253 associated with functional magnetic resonance imaging detectable hypoxia, limited drug delivery, and resistance to irinotecan therapy. Clin Cancer Res. December…