AnalyzeDirect Gorantla S, Dou H, Boska M, Destache CJ, Nelson J, Poluektova L, Rabinow BE, Gendelman HE, Mosley RL. Quantitative magnetic resonance and SPECT imaging for macrophage tissue migration and nanoformulated drug delivery. J Leukoc Biol. November 2006;80(5):1165-1174.
Full Text – Open Access
Publication Date
November 2006
How Analyze was Used
“Reconstructed SPECT images (green) were coregistered and overlaid to MRI scans (red) using the Analyze package (AnalyzeDirect, Inc., Lenexa, KS).”
Keywords
Adoptive Transfer
Animals
Bone Marrow/chemistry
Cell Movement/physiology
Dextrans
Drug Carriers/chemistry/pharmacokinetics
Drug Delivery Systems
Feasibility Studies
Ferrosoferric Oxide
Indinavir/chemistry/pharmacokinetics
Indium Radioisotopes
Iron/pharmacokinetics
Macrophages/drug effects/physiology/transplantation
Magnetic Resonance Imaging (MRI)/methods
Magnetite Nanoparticles
Male
Mice
Mice, Inbred BALB C
Nanoparticles/chemistry
Organometallic Compounds/pharmacokinetics
Oxides/pharmacokinetics
Oxyquinoline/analogs & derivatives/pharmacokinetics
Tissue Distribution
Tomography, Emission-Computed, Single-Photon (SPECT)/methods
Author Affiliation(s)
Center for Neurovirology and Neurodegenerative Disorders, University of Nebraska Medical Center, Omaha, NE, US. (SG, HD, MB, JN, LP, HEG, RLM)
Department of †Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, US. (SG, HD, MB, JN, LP, HEG, RLM)
Department of Radiology, University of Nebraska Medical Center, Omaha, NE, US. (MB, JN)
School of Pharmacy and Health Professions, Creighton University, Omaha, NE, US. (CJD)
Baxter Healthcare Corporation, Round Lake, IL, US. (BER)
ID# 1863
Tags: Adoptive Transfer, Animals, Bone Marrow/chemistry, Cell Movement/physiology, Dextrans, Drug Carriers/chemistry/pharmacokinetics, Drug Delivery Systems, Feasibility Studies, Ferrosoferric Oxide, Inbred BALB C Mice, Indinavir/chemistry/pharmacokinetics, Indium Radioisotopes, Iron/pharmacokinetics, Macrophages/drug effects/physiology/transplantation, Magnetic Resonance Imaging (MRI)/methods, Magnetite Nanoparticles, Male, Mice, Nanoparticles/chemistry, Organometallic Compounds/pharmacokinetics, Oxides/pharmacokinetics, Oxyquinoline/analogs & derivatives/pharmacokinetics, Single-Photon Emission-Computed Tomography (SPECT)/methods, Tissue Distribution