Tag Archives: Animal Disease Models

Mutations in the Latent TGF-beta Binding Protein 3 (LTBP3) gene cause brachyolmia with amelogenesis imperfecta

Huckert M, Stoetzel C, Morkmued S, Laugel-Haushalter V, Geoffroy V, Muller J, Clauss F, Prasad MK, Obry F, Raymond JL, Switala M, Alembik Y, Soskin S, Mathieu E, Hemmerlé J, Weickert JL, Dabovic B, Rifkin DB, Dheedene A, Boudin E, Caluseriu O, Cholette MC, McLeod R, Antequera R, Gellé MP, Coeuriot JL, Jacquelin LF, Bailleul-Forestier…

Recombinant interleukin-1 receptor antagonist conjugated to superparamagnetic iron oxide nanoparticles for theranostic targeting of experimental glioblastoma

Shevtsov MA, Nikolaev BP, Yakovleva LY, Dobrodumov AV, Zhakhov AV, Mikhrina AL, Pitkin E, Parr MA, Rolich VI, Simbircev AS, Ischenko AM. Recombinant interleukin-1 receptor antagonist conjugated to superparamagnetic iron oxide nanoparticles for theranostic targeting of experimental glioblastoma. Neoplasia. January 2015;17(1):32-42. Full Text – Open Access Publication Date January 2015 How Analyze was Used “For…

Intra-renal delivery of mesenchymal stem cells attenuates myocardial injury after reversal of hypertension in porcine renovascular disease

Eirin A, Zhu XY, Ferguson CM, Riester SM, van Wijnen AJ, Lerman A, Lerman LO. Intra-renal delivery of mesenchymal stem cells attenuates myocardial injury after reversal of hypertension in porcine renovascular disease. Stem Cell Res Ther. January 2015;6(1):7. Full Text – Open Access Publication Date January 2015 How Analyze was Used “Multiple consecutive scans were…

Adipose tissue remodeling in a novel domestic porcine model of diet-induced obesity

Pawar AS, Zhu X-Y, Eirin A, Tang H, Jordan KL, Woollard JR, Lerman A, Lerman LO. Adipose tissue remodeling in a novel domestic porcine model of diet-induced obesity. Obesity. December 2014. Publication Date December 2014 How Analyze was Used “All Images were analyzed with the Analyze™ software package…For LV function, the LV endocardial surfaces were…

Analysis of glioblastoma tumor coverage by oncolytic virus-loaded neural stem cells using MRI-based tracking and histological reconstruction

Morshed RA, Gutova M, Juliano J, Barish ME, Hawkins-Daarud A, Oganesyan D, Vazgen K, Yang T, Annala A, Ahmed AU, Aboody KS, Swanson KR, Moats RA, Lesniak MS. Analysis of glioblastoma tumor coverage by oncolytic virus-loaded neural stem cells using MRI-based tracking and histological reconstruction. Cancer Gene Ther. December 2014. Publication Date December 2014 How…

Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo

Terry MR, Arya R, Mukhopadhyay A, Berrett KC, Clair PM, Witt B, Salama ME, Bhutkar A, Oliver TG. Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo. Cell Death Differ. October 2014. Full Text – Open Access Publication Date October 2014 How Analyze was Used “Images were acquired using Perkin Elmer Quantum FX software and…

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

Chong JJH, Yang X, Don CW, Minami E, Liu YW, Weyers JJ, Mahoney WM, Van Biber B, Cook SM, Palpant NJ, Gantz JA, Fugate JA, Muskheli V, Gough GM, Vogel KW, Astley CA, Hotchkiss CE, Baldessari A, Pabon L, Reinecke H, Gill EA, Nelson V, Kiem HP, Laflamme MA, Murry CE. Human embryonic-stem-cell-derived cardiomyocytes regenerate…

Obesity-metabolic derangement exacerbates cardiomyocyte loss distal to moderate coronary artery stenosis in pigs without affecting global cardiac function

Li ZL, Ebrahimi B, Zhang X, Eirin A, Woollard JR, Tang H, Lerman A, Wang SM, Lerman LO. Obesity-metabolic derangement exacerbates cardiomyocyte loss distal to moderate coronary artery stenosis in pigs without affecting global cardiac function. Am J Physiol Heart Circ Physiol. April 2014;306(7):H1087-1101. Publication Date April 2014 How Analyze was Used “Images were analyzed…

Longitudinal characterization of a model of chronic allergic lung inflammation in mice using imaging, functional and immunological methods

Changani K, Pereira C, Young S, Shaw R, Campbell SP, Pindoria K, Jordan S, Wiley K, Bolton S, Nials T, Haase M, Pedrick M, Knowles R. Longitudinal characterization of a model of chronic allergic lung inflammation in mice using imaging, functional and immunological methods. Clin Sci (Lond). December 2013;125(12):555-564. Full Text – Open Access Publication…

Cerebrospinal fluid pressures resulting from experimental traumatic spinal cord injuries in a pig model

Jones CF, Lee JH, Burstyn U, Okon EB, Kwon BK, Cripton PA. Cerebrospinal fluid pressures resulting from experimental traumatic spinal cord injuries in a pig model. J Biomech Eng. October 2013;135(10):101005. Publication Date October 2013 How Analyze was Used “Images for each section were merged in Adobe Photoshop …, the lesion area and total spinal…