AnalyzeDirect Chong JJH, Yang X, Don CW, Minami E, Liu YW, Weyers JJ, Mahoney WM, Van Biber B, Cook SM, Palpant NJ, Gantz JA, Fugate JA, Muskheli V, Gough GM, Vogel KW, Astley CA, Hotchkiss CE, Baldessari A, Pabon L, Reinecke H, Gill EA, Nelson V, Kiem HP, Laflamme MA, Murry CE. Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts. Nature. June 2014;510(7504):273-277.
Full Text – Open Access
Publication Date
June 2014
How Analyze was Used
“Raw scan data were reconstructed to a 3D slice dataset with an isotropic resolution of 35 μm using the software NRecon V1.6.1.0 …, and analyzed using CTan … and Analyze 10.0.”
Keywords
Animals
Arrhythmias, Cardiac/physiopathology
Calcium/metabolism
Cell Survival
Coronary Vessels/physiology
Cryopreservation
Disease Models, Animal
Electrocardiography
Embryonic Stem Cells/cytology
Heart
Humans
Macaca nemestrina
Male
Mice
Myocardial Infarction/pathology/therapy
Myocytes, Cardiac/cytology
Regeneration
Regenerative Medicine/methods
Author Affiliation(s)
Center for Cardiovascular Biology, University of Washington, Seattle, Washington 98109, US. (JJHC, XY, EM, YWL, JJW, WMM, BVB, NJP, JAG, JAF, VM, LP, HR, MAL, CEM)
Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, US. (JJHC, XY, EM, YWL, JJW, WMM, BVB, NJP, JAG, JAF, VM, LP, HR, MAL, CEM)
Department of Cardiology Westmead Hospital, Westmead, New South Wales 2145, Australia. (JJHC)
School of Medicine, University of Sydney, Sydney, New South Wales 2006, Australia. (JJHC)
Department of Pathology, University of Washington, Seattle, WA 98195, US. (JJHC, XY, EM, YWL, JJW, WMM, BVB, NJP, JAG, JAF, VM, LP, HR, HPK, MAL, CEM)
Department of Medicine/Cardiology, University of Washington, Seattle, WA 98195, US. (CWD, EM, EAG, CEM)
Department of Comparative Medicine, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, US. (SMC)
Department of Bioengineering, University of Washington, Seattle, WA 98195, US. (JAG, CEM)
Washington National Primate Research Center, University of Washington, Seattle, WA 98195, US. (GMG, KWV, CAA, CEH, AB)
Fred Hutchinson Cancer Research Center, Seattle, WA 98109, US. (VN, HPK)
ID# 1636
Tags: Animal Disease Models, Animals, Calcium/metabolism, Cardiac Arrhythmias/physiopathology, Cardiac Myocytes/cytology, Cell Survival, Coronary Vessels/physiology, Cryopreservation, Electrocardiography, Embryonic Stem Cells/cytology, Heart, Humans, Macaca nemestrina, Male, Mice, Myocardial Infarction/pathology/therapy, Regeneration, Regenerative Medicine/methods