AnalyzeDirect Filvaroff EH, Guillet S, Zlot C, Bao M, Ingle G, Steinmetz H, Hoeffel J, Bunting S, Ross J, Carano RA, Powell-Braxton L, Wagner GF, Eckert R, Gerritsen ME, French DM. Stanniocalcin 1 alters muscle and bone structure and function in transgenic mice. Endocrinology. September 2002;143(9):3681-3690.
Full Text – Open Access
Publication Date
September 2002
How Analyze was Used
“The femoral cortical bone volume, total volume, and density were determined by application of an automated image segmentation algorithm constructed from the Analyze (AnalyzeDirect Inc., Lenexa, KS) image analysis software libraries.”
Keywords
Animals
Body Composition
Body Constitution
Bone Density
Bone Development
Bone Matrix/metabolism
Bone and Bones/anatomy & histology/physiology
Calcification, Physiologic
Calcium/blood
Cartilage/metabolism
Female
Gene Expression
Glycoproteins/genetics/physiology
Growth/genetics
Growth Plate/anatomy & histology
Hormones/genetics/physiology
Male
Mice
Mice, Transgenic
Microscopy, Electron
Muscle, Skeletal/anatomy & histology/physiology
Neovascularization, Physiologic
Osteoclasts/physiology
Skull/radiography
Tomography, X-Ray Computed (CT)
Author Affiliation(s)
Department of Molecular Oncology, Genentech Inc., South San Francisco, CA 94080, US. (EHF, MB)
Department of Pathology, Genentech Inc., South San Francisco, CA 94080, US. (SG, DMF)
Department of Physiology, Genentech Inc., South San Francisco, CA 94080, US. (CZ, GI, HS, JH, SB, JR, RADC, LPB, MEG)
Department of Safety Assessment, Genentech Inc., South San Francisco, CA 94080, US. (RE)
Department of Physiology, Faculty of Medicine and Dentistry, The University of Western Ontario, London, Ontario N6A 5C1, Canada. (GFW)
ID# 2552
Tags: Animals, Body Composition, Body Constitution, Bone and Bones/anatomy & histology/physiology, Bone Density, Bone Development, Bone Matrix/metabolism, Calcium/blood, Cartilage/metabolism, Electron Microscopy, Female, Gene Expression, Glycoproteins/genetics/physiology, Growth Plate/anatomy & histology, Growth/genetics, Hormones/genetics/physiology, Male, Mice, Osteoclasts/physiology, Physiologic Calcification, Physiologic Neovascularization, Skeletal Muscle/anatomy & histology/physiology, Skull/radiography, Transgenic Mice, X-Ray Computed Tomography (CT)