Martina Buccardi et al. Regional micro-CT analysis enables longitudinal detection of compensatory ventilation effects in a mouse model of pulmonary fibrosis American Journal of Respiratory Cell and Molecular Biology.
Publication Date
February 24, 2026
How Analyze was Used
“A multi-resolution strategy combined low-resolution coarse mapping with a high-resolution 2.5D CNN for fine segmentation; outputs were merged by voting, achieving a Dice coefficient of ~0.97 in validation. Airways were semi-automatically segmented (AnalyzeDirect, Overland Park, KS).”
Keywords
Micro-computed tomography, Bleomycin model, Regional analysis, Lung fibrosis, Drug discovery, Imaging biomarkers
Author Affiliation(s)
Chiesi Farmaceutici, Parma, Italy
AnalyzeDirect