AnalyzeDirect Wengenack TM, Reyes DA, Curran GL, Borowski BJ, Lin J, Preboske GM, Holasek SS, Gilles EJ, Chamberlain R, Marjanska M, Jack CR, Jr., Garwood M, Poduslo JF. Regional differences in MRI detection of amyloid plaques in AD transgenic mouse brain. Neuroimage. January 2011;54(1):113-122.
Full Text – Open Access
Publication Date
January 2011
How Analyze was Used
“Anatomic spatial co-registration between T2SE and T2*GE MRI scans and the corresponding histological sections of the same mouse was accomplished using image analysis software with a linked cursor system (Analyze, AnalyzeDirect, Overland Park, KS) (Robb, 1990).”
Keywords
Alzheimer Disease/genetics/metabolism/pathology
Amyloid Precursor Protein Secretases/genetics
Animals
Cerebral Cortex/anatomy & histology/pathology
Hippocampus/anatomy & histology/pathology
Humans
Iron/metabolism
Magnetic Resonance Imaging/ (MRI)methods
Mice
Mice, Transgenic
Organ Specificity
Plaque, Amyloid/pathology
Thalamus/anatomy & histology/pathology
Author Affiliation(s)
Molecular Neurobiology Laboratory, Departments of Neurology, Neuroscience, and Biochemistry/Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55905, US. (TMW, GLC, SSH, EJG, JFP)
Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, US. (DAR, BJB, GMP, CRJ)
Center for Magnetic Resonance Research and Department of Radiology, University of Minnesota Medical School, Minneapolis, MN 55455, US. (JL, RC, MM, MGP)
ID# 833
Tags: Alzheimer Disease/genetics/metabolism/pathology, Amyloid Plaque/pathology, Amyloid Precursor Protein Secretases/genetics, Animals, Cerebral Cortex/anatomy & histology/pathology, Hippocampus/anatomy & histology/pathology, Humans, Iron/metabolism, Magnetic Resonance Imaging (MRI)/methods, Mice, Organ Specificity, Thalamus/anatomy & histology/pathology, Transgenic Mice